LOXL2 Protein (AA 26-774) (His tag)
LOXL2
宿主: 人
宿主: HEK-293 Cells
Recombinant
>95 % as determined by reduced SDS-PAGE.
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- 抗原 See all LOXL2 蛋白
- LOXL2 (Lysyl Oxidase-Like 2 (LOXL2))
- 蛋白类型
- Recombinant
- 产品特性
- AA 26-774
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This LOXL2 protein is labelled with His tag.
- 原理
- Human LOXL2 Protein, His Tag (active enzyme)
- 纯度
- >95 % as determined by reduced SDS-PAGE.
- 内毒素水平
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product LOXL2 蛋白
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Lysyl Oxidase-Like 2 (LOXL2) (AA 675-773) protein (GST tag)
LOXL2 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Lysyl Oxidase-Like 2 (LOXL2) (AA 26-776) protein (His tag)LOXL2 宿主: 小鼠 宿主: 酵母菌 Recombinant > 90 % SDS
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- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- 20 mM MES, 50 mM NaCl, pH 6.5
- 储存条件
- -80 °C
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- 抗原
- LOXL2 (Lysyl Oxidase-Like 2 (LOXL2))
- 别名
- LOXL2 (LOXL2 产品)
- 别名
- LOR2 Protein, WS9-14 Protein, CG4402 Protein, Dmel\\CG4402 Protein, Dmloxl-2 Protein, dmlox-2 Protein, 1110004B06Rik Protein, 4930526G11Rik Protein, 9430067E15Rik Protein, GB13360 Protein, lox2-like Protein, LOXL2 Protein, lor2 Protein, loxl-2 Protein, ws9-14 Protein, im:7136137 Protein, si:dkeyp-32b1.1 Protein, wu:fk12g04 Protein, zgc:158414 Protein, lysyl oxidase like 2 Protein, lysyl oxidase-like 2 Protein, lysyl oxidase homolog 4 Protein, lysyl oxidase like 2 L homeolog Protein, lysyl oxidase-like 2b Protein, LOXL2 Protein, lox2 Protein, Loxl2 Protein, LOC408544 Protein, loxl2.L Protein, loxl2 Protein, loxl2b Protein
- 背景
- Lysyl oxidase homolog 2 is also known as LOXL2, Lysyl oxidase-like protein 2, which is expressed in many tissues, highest expression in reproductive tissues, placenta, uterus and prostate, Up-regulated in a number of cancers cells and tissues. LOXL2 mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine). When secreted in extracellular matrix, promotes cross-linking of extracellular matrix proteins by mediating oxidative deamination of peptidyl lysine residues in precursors to fibrous collagen and elastin. LOXL2 acts as a regulator of sprouting angiogenesis, probably via collagen IV scaffolding. When nuclear, acts as a transcription corepressor and specifically mediates deamination of trimethylated 'Lys-4' of histone H3 (H3K4me3), a specific tag for epigenetic transcriptional activation. LOXL2 acts as a regulator of chondrocyte differentiation, probably by regulating expression of factors that control chondrocyte differentiation.
- 分子量
- 86.0 kDa
- NCBI登录号
- NP_002309
- 途径
- Chromatin Binding
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