IL12A & IL27B (AA 20-189) (Active) protein (His tag)
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- 抗原
- IL12A & IL27B
- 蛋白类型
- Recombinant
- 生物活性
- Active
- 产品特性
- AA 20-189
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宿主
- 人, 大鼠
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资源
- HEK-293 Cells
- 标记
- His tag
- 原理
- Human IL-23 alpha & Rat IL-12 beta Heterodimer Protein, His Tag&Tag Free (MALS verified)
- 纯度
- >90 % as determined by SDS-PAGE.
- 内毒素水平
- Less than 1.0 EU per μg by the LAL method.
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IL12A & IL27B (AA 22-196) (Active) protein (His tag)
宿主: 小鼠 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Func Active
IL12A & IL27B (AA 20-189) (Active) protein (His tag)宿主: 人, 小鼠 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Func Active
IL12A & IL27B (AA 20-189) (Active) protein (His tag)宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Func Active
IL12A & IL27B (AA 20-189) (Active) protein (His tag,AVI tag,Biotin)宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Func Active
IL12A & IL27B (AA 22-189) (Active) protein (His tag)宿主: 小鼠, Cynomolgus 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- PBS, pH 7.4
- 储存条件
- -20 °C
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- 抗原
- IL12A & IL27B
- 别名
- IL23A & IL12B
- 背景
- Interleukin-23 subunit alpha (IL-23 alpha) can associates with IL12B to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis.
- 分子量
- 20.6 kDa, 35.9 kDa
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