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CD39 Protein (AA 38-478) (His tag,AVI tag,Biotin)

ENTPD1 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
产品编号 ABIN6972989
发货至: 中国
  • 抗原 See all CD39 (ENTPD1) 蛋白
    CD39 (ENTPD1) (Ectonucleoside Triphosphate diphosphohydrolase 1 (ENTPD1))
    蛋白类型
    Recombinant
    产品特性
    AA 38-478
    宿主
    • 13
    • 5
    • 1
    资源
    • 8
    • 4
    • 2
    • 2
    • 2
    • 1
    HEK-293 Cells
    标记
    This CD39 protein is labelled with His tag,AVI tag,Biotin.
    特异性
    Biotinylation of this product is performed using Avitag™ technology. Briefly, the single lysine residue in the Avitag is enzymatically labeled with biotin.
    产品特性
    Biotinylated Human CD39 / ENTPD1 Protein, His,Avitag™ (MALS verified) (active enzyme)
    纯度
    >95 % as determined by SDS-PAGE.
    内毒素水平
    Less than 1.0 EU per μg by the LAL method.
    Top Product
    Discover our top product ENTPD1 蛋白
  • 应用备注
    MALS verified
    说明

    Ready-to-use Avitag™ biotinylated protein:
    The product is exclusively produced using the Avitag™ technology. Briefly, a unique 15 amino acid peptide, the Avi tag, is introduced into the recombinant protein during expression vector construction. The single lysine residue in the Avi tag is enzymatically biotinylated by the E. Coli biotin ligase BirA.

    This single-point enzymatic labeling technique brings many advantages for commonly used binding assays. The biotinylation happens on the lysine residue of Avi tag, and therefore does NOT interfere with the target protein's natural binding activities. In addition, when immobilized on an avidin-coated surface, the protein orientation is uniform because the position of the Avi tag in the protein is precisely controlled.

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    20 mM Tris, 150 mM NaCl, pH 8.0
    储存条件
    -80 °C
  • 抗原
    CD39 (ENTPD1) (Ectonucleoside Triphosphate diphosphohydrolase 1 (ENTPD1))
    别名
    CD39 (ENTPD1 产品)
    别名
    ATPDase Protein, CD39 Protein, NTPDase-1 Protein, MGC80631 Protein, zgc:100819 Protein, entpd1 Protein, MGC79567 Protein, 2610206B08Rik Protein, AA408691 Protein, Cd39 Protein, ectonucleoside triphosphate diphosphohydrolase 1 Protein, ectonucleoside triphosphate diphosphohydrolase 1 L homeolog Protein, ENTPD1 Protein, Entpd1 Protein, entpd1.L Protein, entpd1 Protein
    背景
    CD39 is also known as Ectonucleoside triphosphate diphosphohydrolase 1, ENTPD1, NTPDase 1, Ecto-ATPDase 1, in the nervous system, could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. Could also be implicated in the prevention of platelet aggregation by hydrolyzing platelet-activating ADP to AMP. Hydrolyzes ATP and ADP equally well. NTPDase-1 was originally described as CD39, a B lymphocyte cell surface marker, but it is also present on the surface of natural killer cells, T cells, and some endothelial cells.Regulatory T cells(Tregs) mediate immunosuppression through multiple, non-redundant, cell-contact dependent and independent mechanisms, a growing body of evidence suggests an important role for the CD39-CD73-adenosine pathway. CD39 ectonucleotidase is the rate-limiting enzyme of a cascade leading to the generation of suppressive adenosine that alters CD4 and CD8 T cell and natural killer cell antitumor activities.
    分子量
    54.0 kDa
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