CD39 Protein (His tag)
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- 抗原 See all CD39 (ENTPD1) 蛋白
- CD39 (ENTPD1) (Ectonucleoside Triphosphate diphosphohydrolase 1 (ENTPD1))
- 蛋白类型
- Recombinant
- 生物活性
- Active
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宿主
- 小鼠
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资源
- Baculovirus infected Insect Cells
- 标记
- This CD39 protein is labelled with His tag.
- 原理
- Recombinant Mouse CD39/ENTPD1 Protein (His Tag)(Active)
- 序列
- Thr 38-Ile 478
- 产品特性
- A DNA sequence encoding the mouse ENTPD1 (P55772) extracellular domain (Thr 38-Ile 478) was fused with a polyhistidine tag at the C-terminus and a signal peptide at the N-terminus.
- 纯度
- > 95 % as determined by SDS-PAGE
- 内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
- Biological Activity Comment
- Measured by its ability to hydrolyze the 5'phosphategroups from the substrate adenosine 5'triphosphate(ATP).The specific activity is > 25,000 pmoles/min/μg.
- Top Product
- Discover our top product ENTPD1 蛋白
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Ectonucleoside Triphosphate diphosphohydrolase 1 (ENTPD1) (AA 38-478) protein (His tag)
ENTPD1 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Ectonucleoside Triphosphate diphosphohydrolase 1 (ENTPD1) (AA 70-197) protein (His-IF2DI Tag)ENTPD1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Ectonucleoside Triphosphate diphosphohydrolase 1 (ENTPD1) (AA 1-510) protein (GST tag)ENTPD1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Ectonucleoside Triphosphate diphosphohydrolase 1 (ENTPD1) (AA 1-510) protein (Strep Tag)Crystallography grade ENTPD1 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Ectonucleoside Triphosphate diphosphohydrolase 1 (ENTPD1) (AA 1-510) protein (Strep Tag)Crystallography grade ENTPD1 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Ectonucleoside Triphosphate diphosphohydrolase 1 (ENTPD1) (AA 38-478) protein (His tag)Crystallography grade ENTPD1 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Ectonucleoside Triphosphate diphosphohydrolase 1 (ENTPD1) (AA 38-478) protein (His tag)Crystallography grade ENTPD1 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Ectonucleoside Triphosphate diphosphohydrolase 1 (ENTPD1) (AA 38-478) (Active) protein (His tag)ENTPD1 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Ectonucleoside Triphosphate diphosphohydrolase 1 (ENTPD1) (AA 38-478) (Active) protein (mFc Tag)ENTPD1 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile 20 mM Tris, 500 mM NaCl, pH 7.4, 10 % glycerol
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- CD39 (ENTPD1) (Ectonucleoside Triphosphate diphosphohydrolase 1 (ENTPD1))
- 别名
- CD39/ENTPD1 (ENTPD1 产品)
- 别名
- ATPDase Protein, CD39 Protein, NTPDase-1 Protein, MGC80631 Protein, zgc:100819 Protein, entpd1 Protein, MGC79567 Protein, 2610206B08Rik Protein, AA408691 Protein, Cd39 Protein, ectonucleoside triphosphate diphosphohydrolase 1 Protein, ectonucleoside triphosphate diphosphohydrolase 1 L homeolog Protein, ENTPD1 Protein, Entpd1 Protein, entpd1.L Protein, entpd1 Protein
- 背景
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Background: CD39, also known as ENTPD1, belongs to the GDA1/CD39 NTPase family. It is expressed primarily on activated lymphoid cells and can also be detected in endothelial tissues. The vascular isoform and the placental isoform II are present in both placenta and umbilical vein, whereas placental isoform I is present in placenta only. CD39 can hydrolyze both nucleoside triphosphates and diphosphates. It is the dominant ecto nucleotidase of vascular and placental trophoblastic tissues and appears to modulate the functional expression of type 2 purinergic (P2) G protein coupled receptors (GPCRs). CD39 transgenic mice exhibit impaired platelet aggregation, prolonged bleeding times, and resistance to systemic thromboembolism. There is a correlation between ATP hydrolysis and triglycerides in patients with chronic heart disease, suggesting a relationship between ATP diphosphohydrolase and thrombogenesis. In the nervous system, CD39 could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission.
Synonym: Ectonucleoside triphosphate diphosphohydrolase 1, NTPDase 1, NTPDase 1, Ecto-ATP diphosphohydrolase 1, Ecto-ATPDase 1, Ecto-ATPase 1, Ecto-apyrase, Lymphoid cell activation antigen, CD39
- 分子量
- 51 kDa
- UniProt
- P55772
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