ANGPTL3 Protein (AA 17-220) (His tag,AVI tag,Biotin)
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- 抗原 See all ANGPTL3 蛋白
- ANGPTL3 (Angiopoietin-Like 3 (ANGPTL3))
- 蛋白类型
- Recombinant
- 生物活性
- Active
- 产品特性
- AA 17-220
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This ANGPTL3 protein is labelled with His tag,AVI tag,Biotin.
- 特异性
- Biotinylation of this product is performed using Avitag™ technology. Briefly, the single lysine residue in the Avitag is enzymatically labeled with biotin.
- 产品特性
- Biotinylated Human Angiopoietin-like 3 / ANGPTL3 Protein, His,Avitag™
- 纯度
- >90 % as determined by SDS-PAGE.
- 内毒素水平
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product ANGPTL3 蛋白
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Angiopoietin-Like 3 (ANGPTL3) (AA 17-219) protein (His-Avi Tag)
ANGPTL3 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Angiopoietin-Like 3 (ANGPTL3) protein (His-Avi Tag,Biotin)ANGPTL3 宿主: 人 宿主: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE
Angiopoietin-Like 3 (ANGPTL3) protein (His tag)ANGPTL3 宿主: 小鼠 宿主: 人细胞 Recombinant > 95 % as determined by reducing SDS-PAGE.
Angiopoietin-Like 3 (ANGPTL3) (AA 17-460) protein (GST tag)ANGPTL3 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Angiopoietin-Like 3 (ANGPTL3) (AA 361-460) protein (GST tag)ANGPTL3 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Angiopoietin-Like 3 (ANGPTL3) protein (Fc Tag)ANGPTL3 宿主: 人 宿主: 人细胞 Recombinant >95 % as determined by reducing SDS-PAGE.
Angiopoietin-Like 3 (ANGPTL3) (AA 17-221) protein (His tag)Crystallography grade ANGPTL3 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Angiopoietin-Like 3 (ANGPTL3) (AA 17-224) protein (His tag)Crystallography grade ANGPTL3 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Angiopoietin-Like 3 (ANGPTL3) (AA 17-460) protein (His tag)Crystallography grade ANGPTL3 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Angiopoietin-Like 3 (ANGPTL3) (AA 17-224) protein (His tag)Crystallography grade ANGPTL3 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
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- 说明
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Ready-to-use Avitag™ biotinylated protein:
The product is exclusively produced using the Avitag™ technology. Briefly, a unique 15 amino acid peptide, the Avi tag, is introduced into the recombinant protein during expression vector construction. The single lysine residue in the Avi tag is enzymatically biotinylated by the E. Coli biotin ligase BirA.
This single-point enzymatic labeling technique brings many advantages for commonly used binding assays. The biotinylation happens on the lysine residue of Avi tag, and therefore does NOT interfere with the target protein's natural binding activities. In addition, when immobilized on an avidin-coated surface, the protein orientation is uniform because the position of the Avi tag in the protein is precisely controlled. - 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- PBS, pH 7.4
- 储存条件
- -20 °C
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- 抗原
- ANGPTL3 (Angiopoietin-Like 3 (ANGPTL3))
- 别名
- Angiopoietin-like 3 (ANGPTL3 产品)
- 别名
- fb60e11 Protein, fb66h02 Protein, wu:fb60e11 Protein, wu:fb66h02 Protein, zgc:111943 Protein, ANGPTL3 Protein, LOC100230785 Protein, ANG-5 Protein, ANGPT5 Protein, ANL3 Protein, FHBL2 Protein, hypl Protein, angiopoietin-like 3 Protein, angiopoietin like 3 Protein, angptl3 Protein, ANGPTL3 Protein, Angptl3 Protein
- 背景
- Angiopoietin-like protein 3 (ANGPTL3) is also known as Angiopoietin-related protein 3, Angiopoietin-5 (ANGPT5 / ANG-5), is a member of the angiopoietin-like family of secreted factors. ANGPTL3 / ANGPT5 is predominantly expressed in the liver, and has the characteristic structure of angiopoietins, consisting of a signal peptide, N-terminal coiled-coil domain and the C-terminal fibrinogen (FBN)-like domain. The FBN-like domain in angiopoietin-like 3 protein was shown to bind alpha-5/beta-3 integrins, and this binding induced endothelial cell adhesion and migration. This protein may also play a role in the regulation of angiogenesis. Angptl3 also acts as dual inhibitor of lipoprotein lipase (LPL) and endothelial lipase (EL), and increases plasma triglyceride and HDL cholesterol in rodents. ANGPTL3 inhibit endothelial lipase to catalyze HDL-phospholipid and increase HDL-PL levels. Circulating PL-riched HDL particles have high cholesterol efflux abilities.
- 分子量
- 27.4 kDa
- NCBI登录号
- NP_055310
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