ANGPTL3 Protein (AA 17-220) (Fc Tag)
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Quick Overview for ANGPTL3 Protein (AA 17-220) (Fc Tag) (ABIN7319869)
抗原
See all ANGPTL3 蛋白蛋白类型
宿主
资源
纯度
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产品特性
- AA 17-220
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标记
- This ANGPTL3 protein is labelled with Fc Tag.
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原理
- Recombinant Human Angiopoietin-related Protein 3/ANGPTL3 (C-Fc)
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序列
- Ser17-Pro220
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产品特性
- Recombinant Human Angiopoietin-related Protein 3 is produced by our Mammalian expression system and the target gene encoding Ser17-Pro220 is expressed with a Fc tag at the C-terminus.
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过滤
- 0.2 μm filtered
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内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
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Biological Activity Comment
- Not validated for activity
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Angiopoietin-Like 3 (ANGPTL3) (AA 17-219) (Active) protein (His-Avi Tag)
ANGPTL3 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE Active
Angiopoietin-Like 3 (ANGPTL3) (AA 17-219) (Active) protein (Biotin,His-Avi Tag)ANGPTL3 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE Active
Angiopoietin-Like 3 (ANGPTL3) (AA 17-460) protein (GST tag)ANGPTL3 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Angiopoietin-Like 3 (ANGPTL3) (AA 17-221) protein (His tag)ANGPTL3 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. ScA, IA, ADA, AM
Angiopoietin-Like 3 (ANGPTL3) (AA 17-460) protein (His tag)ANGPTL3 宿主: 人 宿主: Baculovirus infected Insect Cells Recombinant > 90 % SDS
Angiopoietin-Like 3 (ANGPTL3) (AA 17-206) protein (His tag)ANGPTL3 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Angiopoietin-Like 3 (ANGPTL3) (AA 17-220) (Active) protein (His tag,AVI tag,Biotin)ANGPTL3 宿主: 人 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
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Lyophilized from a 0.2 μm filtered solution of PBS, 5 % Trehalose, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization. -
储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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有效期
- 12 months
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- ANGPTL3 (Angiopoietin-Like 3 (ANGPTL3))
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别名
- Angiopoietin-related protein 3
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背景
- ANG-5,ANGPT5,ANGPTL3,Angiopoietin-5,Angiopoietin-like protein 3,Angiopoietin-related protein 3,Angiopoietin-like 3 (ANGPTL3) is a secreted glycoprotein that is structurally related to the angiopoietins. Mature human ANGPTL3 contains an N-terminal coiled coil domain and a C-terminal fibrinogen-like domain. ANGPTL3 is expressed in the liver from early in development through adulthood. Full length ANGPTL3 circulates in the plasma as do the proteolytically separated N-and C-terminal segments containing the coiled coil domain and fibrinogen-like domains,respectively. ANGPTL3 directly inhibits lipoprotein lipase (LPL) and endothelial lipase (EL), enzymes responsible for hydrolyzing circulating triglycerides and HDL phospholipids. ANGPTL3 promotes an increase in circulating triglyceride levels without altering VLDL or HDL secretion or uptake. ANGPTL3 expression in vivo is up-regulated by LXR agonists and down-regulated by insulin, leptin, and agonists of TRβ or PPARβ.
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分子量
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Calculated MW: 50.7 kDa
Observed MW: 60-70 kDa
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基因ID
- 27329
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UniProt
- Q9Y5C1
抗原
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