ADAM17 Protein (Fc Tag)
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- 抗原 See all ADAM17 蛋白
- ADAM17 (ADAM Metallopeptidase Domain 17 (ADAM17))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This ADAM17 protein is labelled with Fc Tag.
- 序列
- ADAM17 (Lys215-Asn671)+hFc(GLU99-ALA330)
- 产品特性
- Tagged Protein: C-Human Fc tag
- 纯化方法
- affinity purification
- Top Product
- Discover our top product ADAM17 蛋白
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ADAM Metallopeptidase Domain 17 (ADAM17) (AA 752-824) protein (His-IF2DI Tag)
ADAM17 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
ADAM Metallopeptidase Domain 17 (ADAM17) (AA 215-314) protein (GST tag)ADAM17 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
ADAM Metallopeptidase Domain 17 (ADAM17) (AA 693-824) protein (His tag)Crystallography grade ADAM17 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
ADAM Metallopeptidase Domain 17 (ADAM17) (AA 693-827) protein (His tag)Crystallography grade ADAM17 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
ADAM Metallopeptidase Domain 17 (ADAM17) (AA 215-671) protein (His tag)Crystallography grade ADAM17 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
ADAM Metallopeptidase Domain 17 (ADAM17) (AA 215-671) protein (His tag)Crystallography grade ADAM17 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
ADAM Metallopeptidase Domain 17 (ADAM17) (AA 215-824) protein (rho-1D4 tag)Crystallography grade ADAM17 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
ADAM Metallopeptidase Domain 17 (ADAM17) (AA 215-827) protein (rho-1D4 tag)Crystallography grade ADAM17 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Reconstitute with deionized water
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- 储存液
- Without preservative
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C for 12 months (Avoid repeated freezing and thawing)
- 有效期
- 12 months
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- 抗原
- ADAM17 (ADAM Metallopeptidase Domain 17 (ADAM17))
- 别名
- ADAM17 (ADAM17 产品)
- 别名
- ADAM18 Protein, CD156B Protein, CSVP Protein, NISBD Protein, TACE Protein, CD156b Protein, Tace Protein, adam17 Protein, si:dkey-81b15.2 Protein, adam18 Protein, cd156b Protein, csvp Protein, tace Protein, fc20b01 Protein, wu:fc20b01 Protein, zgc:63886 Protein, ADAM metallopeptidase domain 17 Protein, a disintegrin and metallopeptidase domain 17 Protein, ADAM metallopeptidase domain 17b Protein, ADAM metallopeptidase domain 17 L homeolog Protein, ADAM metallopeptidase domain 17a Protein, ADAM17 Protein, Adam17 Protein, adam17b Protein, adam17.L Protein, adam17a Protein
- 背景
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Synonymes: ADAM18, CD156B, CSVP, NISBD, NISBD1, TACE
Description: This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biologic processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The encoded preproprotein is proteolytically processed to generate the mature protease. The encoded protease functions in the ectodomain shedding of tumor necrosis factor-alpha, in which soluble tumor necrosis factor-alpha is released from the membrane-bound precursor. This protease also functions in the processing of numerous other substrates, including cell adhesion proteins, cytokine and growth factor receptors and epidermal growth factor (EGF) receptor ligands. The encoded protein also plays a prominent role in the activation of the Notch signaling pathway. Elevated expression of this gene has been observed in specific cell types derived from psoriasis, rheumatoid arthritis, multiple sclerosis and Crohn's disease patients, suggesting that the encoded protein may play a role in autoimmune disease. [provided by RefSeq, Feb 2016] - 分子量
- 75.79 kDa
- UniProt
- P78536
- 途径
- Notch Signaling, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Response to Growth Hormone Stimulus
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