Neuregulin 1 Protein (NRG1) (Fc Tag)
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- 抗原 See all Neuregulin 1 (NRG1) 蛋白
- Neuregulin 1 (NRG1)
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This Neuregulin 1 protein is labelled with Fc Tag.
- 应用范围
- ELISA
- 原理
- Recombinant human NRG1 Protein with C-terminal Human Fc tag
- 特异性
- NRG1 (Ser20-Arg242) hFc (Glu99-Ala330)
- 产品特性
- Extracellular Domain Protein
- 纯化方法
- affinity purification
- 纯度
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Reconstitute with deionized water
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- 储存液
- Without preservative
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- 有效期
- 12 months
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- 抗原
- Neuregulin 1 (NRG1)
- 别名
- NRG1 (NRG1 产品)
- 别名
- 6030402G23Rik Protein, ARIA Protein, D230005F13Rik Protein, GGF Protein, GGFII Protein, HRG Protein, HRGalpha Protein, Hgl Protein, NDF Protein, SMDF Protein, GGF2 Protein, HGL Protein, HRG1 Protein, HRGA Protein, MST131 Protein, NRG-1 Protein, heregulin Protein, nrg1-A Protein, pro-neuregulin-1 Protein, NRG1 Protein, wu:fm70e01 Protein, DKFZp459A1838 Protein, neuregulin 1 Protein, histidine rich glycoprotein Protein, neuregulin 1 L homeolog Protein, Nrg1 Protein, NRG1 Protein, HRG Protein, nrg1.L Protein, nrg1 Protein
- 背景
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Synonymes: ARIA, GGF, GGF2, HGL, HRG, HRG1, HRGA, MST131, MSTP131, NDF, NRG1-IT2, SMDF
Description: The protein encoded by this gene is a membrane glycoprotein that mediates cell-cell signaling and plays a critical role in the growth and development of multiple organ systems. An extraordinary variety of different isoforms are produced from this gene through alternative promoter usage and splicing. These isoforms are expressed in a tissue-specific manner and differ significantly in their structure, and are classified as types I, II, III, IV, V and VI. Dysregulation of this gene has been linked to diseases such as cancer, schizophrenia, and bipolar disorder (BPD). - 分子量
- predicted molecular mass of 50.3 kDa after removal of the signal peptide.The apparent molecular mass of NRG1-hFc is 55-70 kDa due to glycosylation.
- 基因ID
- 3084
- UniProt
- Q02297
- 途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation
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