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ERG Protein (Fc Tag)

ERG 宿主: 人 宿主: HEK-293 Cells Recombinant
产品编号 ABIN6964259
发货至: 中国
  • 抗原 See all ERG 蛋白
    ERG (ERG, ETS transcription factor (ERG))
    蛋白类型
    Recombinant
    宿主
    • 10
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    • 1
    • 1
    资源
    • 3
    • 3
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    HEK-293 Cells
    标记
    This ERG protein is labelled with Fc Tag.
    序列
    ERG(Val280-Glu405)+hFc(Glu99-Ala330)
    产品特性
    Tagged Protein: C-Human Fc tag
    纯化方法
    affinity purification
    Top Product
    Discover our top product ERG 蛋白
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Reconstitute with deionized water
    缓冲液
    Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    储存液
    Without preservative
    储存条件
    -80 °C
    储存方法
    Store at -80°C for 12 months (Avoid repeated freezing and thawing)
    有效期
    12 months
  • 抗原
    ERG (ERG, ETS transcription factor (ERG))
    别名
    ERG (ERG 产品)
    别名
    erg-3 Protein, p55 Protein, erg Protein, erg_A Protein, zgc:103429 Protein, erg_E Protein, ERG Protein, D030036I24Rik Protein, KCNH2 Protein, ERG, ETS transcription factor Protein, v-ets avian erythroblastosis virus E26 oncogene homolog L homeolog Protein, v-ets avian erythroblastosis virus E26 oncogene homolog Protein, v-ets avian erythroblastosis virus E26 oncogene homolog S homeolog Protein, ETS transcription factor Protein, potassium voltage-gated channel subfamily H member 6 Protein, ERG Protein, Erg Protein, erg.L Protein, erg Protein, erg.S Protein, KCNH6 Protein
    背景
    Synonymes: erg-3, p55
    Description: This gene encodes a member of the erythroblast transformation-specific (ETS) family of transcriptions factors. All members of this family are key regulators of embryonic development, cell proliferation, differentiation, angiogenesis, inflammation, and apoptosis. The protein encoded by this gene is mainly expressed in the nucleus. It contains an ETS DNA-binding domain and a PNT (pointed) domain which is implicated in the self-association of chimeric oncoproteins. This protein is required for platelet adhesion to the subendothelium, inducing vascular cell remodeling. It also regulates hematopoesis, and the differentiation and maturation of megakaryocytic cells. This gene is involved in chromosomal translocations, resulting in different fusion gene products, such as TMPSSR2-ERG and NDRG1-ERG in prostate cancer, EWS-ERG in Ewing's sarcoma and FUS-ERG in acute myeloid leukemia. More than two dozens of transcript variants generated from combinatorial usage of three alternative promoters and multiple alternative splicing events have been reported, but the full-length nature of many of these variants has not been determined. [provided by RefSeq, Apr 2014]
    分子量
    49.39 kDa
    UniProt
    P11308
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