CD11b Protein (Fc Tag)
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- 抗原 See all CD11b (ITGAM) 蛋白
- CD11b (ITGAM) (Integrin alpha M (ITGAM))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This CD11b protein is labelled with Fc Tag.
- 序列
- ITGAM(Phe17-Asn1104)+hFc(Glu99-Ala330)
- 产品特性
- Tagged Protein: C-Human Fc tag
- 纯化方法
- affinity purification
- Top Product
- Discover our top product ITGAM 蛋白
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Reconstitute with deionized water
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- 储存液
- Without preservative
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C for 12 months (Avoid repeated freezing and thawing)
- 有效期
- 12 months
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- 抗原
- CD11b (ITGAM) (Integrin alpha M (ITGAM))
- 别名
- ITGAM (ITGAM 产品)
- 别名
- CD11b/CD18 Protein, CR3 Protein, CR3A Protein, Cd11b Protein, F730045J24Rik Protein, Ly-40 Protein, MAC1 Protein, Mac-1 Protein, Mac-1a Protein, CD11B Protein, MAC-1 Protein, MAC1A Protein, MO1A Protein, SLEB6 Protein, C3bi Protein, integrin subunit alpha M Protein, integrin alpha M Protein, integrin, alpha M (complement component 3 receptor 3 subunit) Protein, integrin alpha-M Protein, ITGAM Protein, Itgam Protein, LOC100351865 Protein
- 背景
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Synonymes: CD11B, CR3A, MAC-1, MAC1A, MO1A, SLEB6
Description: This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. - 分子量
- 145.2 kDa
- UniProt
- P11215
- 途径
- Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
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