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CD11b Protein (Fc Tag)

ITGAM 宿主: 人 宿主: HEK-293 Cells Recombinant
产品编号 ABIN6964128
发货至: 中国
  • 抗原 See all CD11b (ITGAM) 蛋白
    CD11b (ITGAM) (Integrin alpha M (ITGAM))
    蛋白类型
    Recombinant
    宿主
    • 10
    • 4
    • 4
    • 1
    资源
    • 10
    • 4
    • 1
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    • 1
    • 1
    HEK-293 Cells
    标记
    This CD11b protein is labelled with Fc Tag.
    序列
    ITGAM(Phe17-Asn1104)+hFc(Glu99-Ala330)
    产品特性
    Tagged Protein: C-Human Fc tag
    纯化方法
    affinity purification
    Top Product
    Discover our top product ITGAM 蛋白
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Reconstitute with deionized water
    缓冲液
    Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    储存液
    Without preservative
    储存条件
    -80 °C
    储存方法
    Store at -80°C for 12 months (Avoid repeated freezing and thawing)
    有效期
    12 months
  • 抗原
    CD11b (ITGAM) (Integrin alpha M (ITGAM))
    别名
    ITGAM (ITGAM 产品)
    别名
    CD11b/CD18 Protein, CR3 Protein, CR3A Protein, Cd11b Protein, F730045J24Rik Protein, Ly-40 Protein, MAC1 Protein, Mac-1 Protein, Mac-1a Protein, CD11B Protein, MAC-1 Protein, MAC1A Protein, MO1A Protein, SLEB6 Protein, C3bi Protein, integrin subunit alpha M Protein, integrin alpha M Protein, integrin, alpha M (complement component 3 receptor 3 subunit) Protein, integrin alpha-M Protein, ITGAM Protein, Itgam Protein, LOC100351865 Protein
    背景
    Synonymes: CD11B, CR3A, MAC-1, MAC1A, MO1A, SLEB6
    Description: This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene.
    分子量
    145.2 kDa
    UniProt
    P11215
    途径
    Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
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