SARS-CoV-2 Spike Protein (RBD) (mFc Tag)
Quick Overview for SARS-CoV-2 Spike Protein (RBD) (mFc Tag) (ABIN6961175)
抗原
See all SARS-CoV-2 Spike 蛋白蛋白类型
宿主
资源
应用范围
纯度
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产品特性
- RBD
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标记
- This SARS-CoV-2 Spike protein is labelled with mFc Tag.
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原理
- Recombinant SARS-CoV-2 (2019-nCoV) S protein RBD with C-terminal mouse Fc tag
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特异性
- S protein RBD (Arg319-Phe541) mFc (Pro99-Lys330)
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产品特性
- Extracellular Domain Protein
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纯化方法
- Purified from cell culture supernatant by affinity chromatography
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
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储存条件
- -20 °C,-80 °C
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储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
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有效期
- 12 months
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: "Microfluidic particle dam for direct visualization of SARS-CoV-2 antibody levels in COVID-19 vaccinees." in: Science advances, Vol. 8, Issue 22, pp. eabn6064, (2022) (PubMed).
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: "Microfluidic particle dam for direct visualization of SARS-CoV-2 antibody levels in COVID-19 vaccinees." in: Science advances, Vol. 8, Issue 22, pp. eabn6064, (2022) (PubMed).
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- SARS-CoV-2 Spike
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物质类
- Viral Protein
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背景
- SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2) also known as Covid19 (2019 Novel Coronavirus) is a virus that causes illnesses ranging from the common cold to severe diseases. The spike protein is a type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which accounts for recognizing the cell surface receptor, ACE2. S2 contains basic elements needed for the membrane fusion. Recent publications indicate that S1-RBD domain can induce virus neutralizing-antibody and T cell response.
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分子量
- predicted molecular mass of 51.3 kDa after removal of the signal peptide.
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基因ID
- 43740568
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UniProt
- P0DTC2
抗原
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