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TNFSF8 Protein (mFc-His Tag)

TNFSF8 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. ELISA
产品编号 ABIN6961111
发货至: 中国
  • 抗原 See all TNFSF8 蛋白
    TNFSF8 (Tumor Necrosis Factor (Ligand) Superfamily, Member 8 (TNFSF8))
    蛋白类型
    Recombinant
    宿主
    • 18
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    • 1
    资源
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    HEK-293 Cells
    标记
    This TNFSF8 protein is labelled with mFc-His Tag.
    应用范围
    ELISA
    原理
    Recombinant human CD30 Ligand Protein with N-terminal mouse Fc and C-terminal 6xHis tag
    特异性
    MFc (Pro99-Lys330) CD30 Ligand (Gln63-Asp234) 6xHis
    产品特性
    Extracellular Domain Protein
    纯化方法
    affinity purification
    纯度
    The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
    Top Product
    Discover our top product TNFSF8 蛋白
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Reconstitute with deionized water
    缓冲液
    Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    储存液
    Without preservative
    储存条件
    -20 °C,-80 °C
    储存方法
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    有效期
    12 months
  • 抗原
    TNFSF8 (Tumor Necrosis Factor (Ligand) Superfamily, Member 8 (TNFSF8))
    别名
    CD30 Ligand (TNFSF8 产品)
    别名
    CD153 Protein, CD30LG Protein, Cd30l Protein, CD30L Protein, TNFRSF8 Protein, TNFSF8 Protein, tumor necrosis factor (ligand) superfamily, member 8 Protein, TNF superfamily member 8 Protein, tumor necrosis factor superfamily member 8 Protein, Tnfsf8 Protein, TNFSF8 Protein
    背景
    Synonymes: CD30-L,CD153,TNFSF8,CD30L,CD30LG,CD153 antigen,CD30 antigen ligand,CD30 Ligand
    Description: The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF8/CD30, which is a cell surface antigen and a marker for Hodgkin lymphoma and related hematologic malignancies. The engagement of this cytokine expressed on B cell surface plays an inhibitory role in modulating Ig class switch. This cytokine was shown to enhance cell proliferation of some lymphoma cell lines, while to induce cell death and reduce cell proliferation of other lymphoma cell lines. The pleiotropic biologic activities of this cytokine on different CD30+ lymphoma cell lines may play a pathophysiologic role in Hodgkin's and some non-Hodgkin's lymphomas. Two transcript variants encoding different isoforms have been found for this gene.
    分子量
    predicted molecular mass of 48.0 kDa after removal of the signal peptide.The apparent molecular mass of mFc-CD30 Ligand-His is 53-70 kDa due to glycosylation.
    基因ID
    944
    UniProt
    P32971
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