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CD276 Protein (CD276) (mFc-His Tag)

CD276 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. ELISA
产品编号 ABIN6961085
发货至: 中国
  • 抗原 See all CD276 蛋白
    CD276
    蛋白类型
    Recombinant
    宿主
    • 27
    • 12
    • 3
    • 2
    资源
    • 28
    • 5
    • 5
    • 3
    • 2
    • 1
    HEK-293 Cells
    标记
    This CD276 protein is labelled with mFc-His Tag.
    应用范围
    ELISA
    原理
    Recombinant human B7-H3 protein with C-terminal mouse Fc and 6xHis tag
    特异性
    B7-H3 (Leu29-Pro245) mFc (Pro99-Lys330) 6xHis
    产品特性
    Extracellular Domain Protein
    纯化方法
    affinity purification
    纯度
    The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
    Top Product
    Discover our top product CD276 蛋白
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Reconstitute with deionized water
    缓冲液
    Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    储存液
    Without preservative
    储存条件
    -20 °C,-80 °C
    储存方法
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    有效期
    12 months
  • 抗原
    CD276
    别名
    B7-H3 (CD276 产品)
    别名
    sc:d0645 Protein, zgc:158279 Protein, 6030411F23Rik Protein, AU016588 Protein, B7RP-2 Protein, B7h3 Protein, B7H3 Protein, 4Ig-B7-H3 Protein, B7-H3 Protein, CD276 molecule Protein, CD276 molecule S homeolog Protein, CD276 antigen Protein, Cd276 molecule Protein, CD276 Protein, cd276.S Protein, cd276 Protein, Cd276 Protein
    背景
    Synonymes: B7-H3, CD276, B7 homolog 3
    Description: The protein encoded by this gene belongs to the immunoglobulin superfamily, and thought to participate in the regulation of T-cell-mediated immune response. Studies show that while the transcript of this gene is ubiquitously expressed in normal tissues and solid tumors, the protein is preferentially expressed only in tumor tissues. Additionally, it was observed that the 3' UTR of this transcript contains a target site for miR29 microRNA, and there is an inverse correlation between the expression of this protein and miR29 levels, suggesting regulation of expression of this gene product by miR29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
    分子量
    predicted molecular mass of 70-75 kDa after removal of the signal peptide.
    基因ID
    80381
    UniProt
    Q5ZPR3
    途径
    Cancer Immune Checkpoints
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