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ACE2 Protein (His tag)

ACE2 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. SDS, ELISA
产品编号 ABIN6952617
发货至: 中国
  • 抗原 See all ACE2 蛋白
    ACE2 (Angiotensin I Converting Enzyme 2 (ACE2))
    蛋白类型
    Recombinant
    宿主
    • 45
    • 7
    • 6
    • 2
    • 2
    • 1
    • 1
    Cynomolgus
    资源
    • 30
    • 11
    • 6
    • 5
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    HEK-293 Cells
    标记
    This ACE2 protein is labelled with His tag.
    应用范围
    SDS-PAGE (SDS), ELISA
    原理
    Cynomolgus ACE2 / ACEH Protein, His Tag
    序列
    AA 18-741
    产品特性
    Cynomolgus ACE2, His Tag is expressed from human 293 cells (HEK293). It contains AA Gln 18 - Thr 741 (Accession # A0A2K5X283-1). Predicted N-terminus: His
    This protein carries a polyhistidine tag at the N-terminus.
    纯度
    >95 % as determined by SDS-PAGE.
    过滤
    0.2 μm filtered
    内毒素水平
    Less than 1.0 EU per μg by the LAL method.
    Top Product
    Discover our top product ACE2 蛋白
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    50 mM Tris, 150 mM NaCl, Arginine, pH 7.5
    注意事项
    Please avoid repeated freeze-thaw cycles.
    储存条件
    -80 °C
    储存方法
    This product is stable after storage at:
    The product MUST be stored at -70°C or lower upon receipt,
    -70°C for 3 months under sterile conditions.
  • 抗原
    ACE2 (Angiotensin I Converting Enzyme 2 (ACE2))
    别名
    ACE2 (ACE2 产品)
    别名
    ACE1 Protein, CD143 Protein, DCP Protein, DCP1 Protein, ICH Protein, MVCD3 Protein, ACEH Protein, 2010305L05Rik Protein, zgc:92514 Protein, angiotensin I converting enzyme Protein, angiotensin I converting enzyme 2 Protein, angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 Protein, ACE Protein, ACE2 Protein, Ace2 Protein, ace2 Protein
    背景
    Angiotensin-converting enzyme 2 (ACE2) is also known as ACEH (ACE homolog), is an integral membrane protein with considerable homologous to ACE, which belongs to the peptidase M2 family. ACE2 is an exopeptidase that catalyses the conversion of angiotensin I to the nonapeptide angiotensin, or the conversion of angiotensin II to angiotensin 1-7. ACE2 may be an important regulator of heart function. In case of human coronaviruses SARS and HCoV-NL63 infections, ACE-2 serve as functional receptor for the spike glycoprotein of both coronaviruses. ACE2 is activated by chloride and fluoride, but not bromide and Inhibited by MLN-4760, cFP_Leu, and EDTA, but not by the ACE inhibitors linosipril, captopril and enalaprilat. ACE2 is active from pH 6 to 9, and the optimum pH is 6.5 in the presence of 1 M NaCl.
    分子量
    85.7 kDa
    NCBI登录号
    XP_005593094
    途径
    ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour
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