CD94 Protein, CD94-B Protein, Cd94 Protein, killer cell lectin like receptor D1 Protein, killer cell lectin-like receptor subfamily D, member 1 Protein, killer cell lectin-like receptor, subfamily D, member 1 Protein, KLRD1 Protein, Klrd1 Protein
背景
CD94(Natural killer cells antigen CD94) is also known as KLRD1, KP43, NK cell receptor, Killer cell lectin-like receptor subfamily D member 1. CD94 plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. KLRD1 (CD94) is an antigen preferentially expressed on NK cells and is classified as a type II membrane protein because it has an external C terminus. CD94 pairs with the NKG2 Molecule as a heterodimer. The CD94/NKG2 complex, on the surface of natural killer cells interacts with Human Leukocyte Antigen (HLA)-E on target cells.