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CD94 Protein (His tag)

KLRD1 宿主: 人 宿主: 人细胞 Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7318806
发货至: 中国
  • 抗原 See all CD94 (KLRD1) 蛋白
    CD94 (KLRD1) (Killer Cell Lectin-Like Receptor Subfamily D, Member 1 (KLRD1))
    蛋白类型
    Recombinant
    宿主
    • 13
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    资源
    • 6
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    人细胞
    标记
    This CD94 protein is labelled with His tag.
    原理
    Recombinant Human KLRD1/CD94 Protein (His Tag)
    序列
    Ser34-Ile179
    产品特性
    Recombinant Human Natural Killer Cells Antigen CD94 is produced by our Mammalian expression system and the target gene encoding Ser34-Ile179 is expressed with a 6His tag at the N-terminus.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product KLRD1 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    CD94 (KLRD1) (Killer Cell Lectin-Like Receptor Subfamily D, Member 1 (KLRD1))
    别名
    KLRD1/CD94 (KLRD1 产品)
    别名
    CD94 Protein, CD94-B Protein, Cd94 Protein, killer cell lectin like receptor D1 Protein, killer cell lectin-like receptor subfamily D, member 1 Protein, killer cell lectin-like receptor, subfamily D, member 1 Protein, KLRD1 Protein, Klrd1 Protein
    背景

    Background: CD94 (Cluster of Differentiation 94), also known as killer cell lectin-like receptor subfamily D member 1 (KLRD1), is expressed on the surface of natural killer cells in the innate immune system. CD94 Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. CD94 Can form disulfide-bonded heterodimer with NKG2 family members. The CD94/NKG2 complex, on the surface of natural killer cells interacts with Human Leukocyte Antigen (HLA)-E on target cells. Natural killer (NK) cells are a distinct lineage of lymphocytes that mediate cytotoxic activity and secrete cytokines upon immune stimulation. Several genes of the C-type lectin superfamily, including members of the NKG2 family, are expressed by NK cells and may be involved in the regulation of NK cell function. KLRD1 (CD94) is an antigen preferentially expressed on NK cells and is classified as a type II membrane protein because it has an external C terminus.

    Synonym: Natural killer cells antigen CD94, KP43, Killer cell lectin-like receptor subfamily D member 1, NK cell receptor, CD94, KLRD1

    分子量
    17.7 kDa
    UniProt
    Q13241
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