ERBB3 Protein (AA 20-643) (His tag,AVI tag,Biotin)
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- 抗原 See all ERBB3 蛋白
- ERBB3 (Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3))
- 蛋白类型
- Recombinant
- 生物活性
- Active
- 产品特性
- AA 20-643
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This ERBB3 protein is labelled with His tag,AVI tag,Biotin.
- 序列
- AA 20-643
- 特异性
- Biotinylation of this product is performed using Avitag™ technology. Briefly, the single lysine residue in the Avitag is enzymatically labeled with biotin.
- 纯度
- >95 % as determined by reduced SDS-PAGE.
- 内毒素水平
- Less than 1.0 EU per μg by the LAL method.
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- Discover our top product ERBB3 蛋白
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Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3) (AA 20-643) protein (His-Avi Tag)
ERBB3 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3) (AA 20-643) protein (Fc Tag)ERBB3 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3) (AA 20-641) protein (His tag)ERBB3 宿主: Cynomolgus, 猕猴 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3) protein (His tag)ERBB3 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3) protein (His-Avi Tag,Biotin)ERBB3 宿主: 人 宿主: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3) (AA 20-643) protein (His tag)ERBB3 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3) protein (mFc Tag)ERBB3 宿主: 人 宿主: 人细胞 Recombinant >95 % as determined by reducing SDS-PAGE.
Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3) (AA 1005-1230) protein (His tag)ERBB3 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3) (AA 21-331) protein (GST tag)ERBB3 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3) (AA 1-130) protein (GST tag)ERBB3 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
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- 说明
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Ready-to-use AvitagTM biotinylated protein:
The product is exclusively produced using the AvitagTM technology. Briefly, a unique 15 amino acid peptide, the Avi tag, is introduced into the recombinant protein during expression vector construction. The single lysine residue in the Avi tag is enzymatically biotinylated by the E. Coli biotin ligase BirA.
This single-point enzymatic labeling technique brings many advantages for commonly used binding assays. The biotinylation happens on the lysine residue of Avi tag, and therefore does NOT interfere with the target protein's natural binding activities. In addition, when immobilized on an avidin-coated surface, the protein orientation is uniform because the position of the Avi tag in the protein is precisely controlled. - 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- PBS, pH 7.4
- 注意事项
- Please avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
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- 抗原
- ERBB3 (Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3))
- 别名
- ErbB3 (ERBB3 产品)
- 别名
- ErbB-3 Protein, HER3 Protein, LCCS2 Protein, MDA-BF-1 Protein, c-erbB-3 Protein, c-erbB3 Protein, erbB3-S Protein, p180-ErbB3 Protein, p45-sErbB3 Protein, p85-sErbB3 Protein, ERBB3 Protein, C76256 Protein, Erbb-3 Protein, Erbb3r Protein, Her3 Protein, nuc-ErbB3 Protein, erb-b2 receptor tyrosine kinase 3 Protein, v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) Protein, ERBB3 Protein, Erbb3 Protein
- 背景
- ErbB3,also known as Her3 (human epidermal growth factor receptor 3), is a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound glycoprotein has a neuregulin binding domain but has not an active kinase domain. It therefore can bind the ligand but cannot mediate the intracellular signal transduction through protein phosphorylation. However, it does form heterodimers with ErbB2 or other EGFR members responsible for tyrosine phosphorylation to give a receptor complex and initiate the related pathway, which lead to cell proliferation or differentiation. Overexpression of this protein has been reported in numerous cancers, including prostate, bladder, and breast tumors. This protein has different isoforms derived from alternative splicing variants, and among which, the secreted isoform lacking the intermembrane region modulates the activity of membrane-bound form.
- 分子量
- 72.4 kDa
- NCBI登录号
- NP_001973
- 途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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