HHLA2 Protein (AA 23-344) (Fc Tag)
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- 抗原 See all HHLA2 蛋白
- HHLA2 (HERV-H LTR-Associating 2 (HHLA2))
- 蛋白类型
- Recombinant
- 生物活性
- Active
- 产品特性
- AA 23-344
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This HHLA2 protein is labelled with Fc Tag.
- 序列
- AA 23-344
- 纯度
- >90 % as determined by reduced SDS-PAGE.
- 内毒素水平
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product HHLA2 蛋白
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- Tris with Glycine, Arginine and NaCl, pH 7.5
- 注意事项
- Please avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
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- 抗原
- HHLA2 (HERV-H LTR-Associating 2 (HHLA2))
- 别名
- B7-H7 (HHLA2 产品)
- 别名
- B7H7 Protein, HERV-H LTR-associating 2 Protein, HHLA2 Protein, hhla2 Protein
- 背景
- B7-H7 (HHLA2) is a newly identified B7 family member that regulates human T-cell functions. B7-H7 was previously known as human endogenous retrovirus-H long terminal repeat associating 2 (HHLA2) with unidentified function. Recently, B7-H7 has been identified as a specific ligand for human CD28H. The B7-H7-CD28H pathway strongly promoted CD4+ T-cell proliferation and cytokine production via an AKT-dependent signaling cascade in the presence of TCR signaling, suggesting B7-H7 comprises a new co-stimulatory pathway. The first IgV domain of B7-H7, which presumably binds to a putative receptor, shows the highest homology to other B7 family members.
- 分子量
- 63.4 kDa
- NCBI登录号
- NP_009003
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