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LRP5 Protein (AA 644-1263) (Fc Tag)

LRP5 宿主: 人 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
产品编号 ABIN6809855
发货至: 中国
  • 抗原 See all LRP5 蛋白
    LRP5 (Low Density Lipoprotein Receptor-Related Protein 5 (LRP5))
    蛋白类型
    Recombinant
    生物活性
    Active
    产品特性
    AA 644-1263
    宿主
    • 9
    • 3
    • 1
    资源
    • 6
    • 4
    • 2
    • 1
    HEK-293 Cells
    标记
    This LRP5 protein is labelled with Fc Tag.
    序列
    AA 644-1263
    纯度
    >90 % as determined by SDS-PAGE.
    内毒素水平
    Less than 0.1 EU per μg by the LAL method.
    Top Product
    Discover our top product LRP5 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    Tris with Glycine, Arginine and NaCl,  pH 7.5
    注意事项
    Please avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
  • Pokharel, Mohanty, Mariasoosai, Miura, Maddison, Natesan, Bose: "Human beta defensin-3 mediated activation of β-catenin during human respiratory syncytial virus infection: interaction of HBD3 with LDL receptor-related protein 5." in: Frontiers in microbiology, Vol. 14, pp. 1186510, (2023) (PubMed).

  • 抗原
    LRP5 (Low Density Lipoprotein Receptor-Related Protein 5 (LRP5))
    别名
    LRP-5 (LRP5 产品)
    别名
    Xlrp5 Protein, bmnd1 Protein, evr1 Protein, evr4 Protein, hbm Protein, lr3 Protein, lrp5-A Protein, lrp7 Protein, oppg Protein, ops Protein, opta1 Protein, vbch2 Protein, LRP5 Protein, LRP6 Protein, BMND1 Protein, EVR1 Protein, EVR4 Protein, HBM Protein, LR3 Protein, LRP7 Protein, OPPG Protein, OPS Protein, OPTA1 Protein, VBCH2 Protein, mKIAA4142 Protein, low-density lipoprotein receptor-related protein 5 Protein, LDL receptor related protein 5 Protein, LDL receptor related protein 5 L homeolog Protein, low density lipoprotein receptor-related protein 5 Protein, LDL receptor related protein 5 like Protein, LOC100147353 Protein, LRP5 Protein, lrp5.L Protein, lrp5 Protein, Lrp5 Protein, LRP5L Protein
    背景
    Low-density lipoprotein receptor-related protein 5(LRP-5) is also known as BMND1, EVR1, EVR4, HBM, LR3, LRP7, OPPG, OPTA1, VBCH2, LDL receptor related protein 5 and PCLD4. LRP5 is a transmembrane low-density lipoprotein receptor that shares a similar structure with LRP6. LRP5 acts as a co-receptor with LRP6 and the Frizzled protein family members for transducing signals by Wnt proteins through the canonical Wnt pathway. This protein plays a key role in skeletal homeostasis. Mutations in LRP5 can lead to considerable changes in bone mass. A loss-of-function mutation causes osteoporosis-pseudoglioma (decrease in bone mass), while a gain-of-function mutation causes drastic increases in bone mass.
    分子量
    96.6 kDa
    NCBI登录号
    NP_002326
    途径
    WNT signaling, Stem Cell Maintenance, Positive Regulation of fat Cell Differentiation
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