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PSMA Protein (AA 44-750) (His tag,AVI tag,Biotin)

FOLH1 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
产品编号 ABIN6731327
发货至: 中国
  • 抗原 See all PSMA (FOLH1) 蛋白
    PSMA (FOLH1) (Folate Hydrolase (Prostate-Specific Membrane Antigen) 1 (FOLH1))
    蛋白类型
    Recombinant
    产品特性
    AA 44-750
    宿主
    • 16
    • 8
    • 3
    • 3
    • 1
    资源
    • 16
    • 7
    • 2
    • 2
    • 2
    • 1
    • 1
    HEK-293 Cells
    标记
    This PSMA protein is labelled with His tag,AVI tag,Biotin.
    序列
    AA 44-750
    特异性
    Biotinylation of this product is performed using Avitag™ technology. Briefly, the single lysine residue in the Avitag is enzymatically labeled with biotin.
    纯度
    >95 % as determined by SDS-PAGE.
    内毒素水平
    Less than 1.0 EU per μg by the LAL method.
    Top Product
    Discover our top product FOLH1 蛋白
  • 说明

    Ready-to-use AvitagTM biotinylated protein:
    The product is exclusively produced using the AvitagTM technology. Briefly, a unique 15 amino acid peptide, the Avi tag, is introduced into the recombinant protein during expression vector construction. The single lysine residue in the Avi tag is enzymatically biotinylated by the E. Coli biotin ligase BirA.

    This single-point enzymatic labeling technique brings many advantages for commonly used binding assays. The biotinylation happens on the lysine residue of Avi tag, and therefore does NOT interfere with the target protein's natural binding activities. In addition, when immobilized on an avidin-coated surface, the protein orientation is uniform because the position of the Avi tag in the protein is precisely controlled.

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    MES and NaCl
    注意事项
    Please avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
  • 抗原
    PSMA (FOLH1) (Folate Hydrolase (Prostate-Specific Membrane Antigen) 1 (FOLH1))
    别名
    PSMA (FOLH1 产品)
    别名
    FGCP Protein, FOLH Protein, GCP2 Protein, GCPII Protein, NAALAD1 Protein, NAALAdase Protein, PSM Protein, PSMA Protein, mGCP Protein, mopsm Protein, Naalad Protein, putative N-acetylated-alpha-linked acidic dipeptidase Protein, folate hydrolase 1B Protein, folate hydrolase 1 Protein, folate hydrolase (prostate-specific membrane antigen) 1 Protein, LOC451185 Protein, FOLH1B Protein, FOLH1 Protein, Folh1 Protein
    背景
    Prostate-specific membrane antigen (PSMA) is also known as Folate hydrolase 1 (FOLH1), Glutamate carboxypeptidase 2 (GCP2), N-acetylated-alpha-linked acidic dipeptidase I (NAALAD1), which belongs to the peptidase M28 family and M28B subfamily. FOLH1 / PSMA is stable at pH greater than 6.5. FOLH1 / PSMA is a type II transmembrane zinc metallopeptidase that is most highly expressed in the nervous system, prostate, kidney, and small intestine. FOLH1 / GCP-2 is homodimer and binds 2 zinc ions per subunit, and required for NAALADase activity. The catalytic activity of PSMA involved in releasing of an unsubstituted, C-terminal glutamyl residue, typically from Ac-Asp-Glu or folylpoly - gamma - glutamates. FOLH1 / GCP-2 / PSMA has both folate hydrolase and N - acetylated - alpha - linked - acidic dipeptidase (NAALADase) activity and has a preference for tri-alpha-glutamate peptides. GCP-2 / PSMA involved in prostate tumor progression and also exhibits a dipeptidyl-peptidase IV type activity. In vitro, cleaves Gly-Pro-AMC.
    分子量
    83.1 kDa
    NCBI登录号
    NP_004467
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