Grancalcin Protein (AA 1-217) (His tag)
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- 抗原 See all Grancalcin (GCA) 蛋白
- Grancalcin (GCA) (Grancalcin, EF-Hand Calcium Binding Protein (GCA))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-217
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宿主
- 人
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资源
- 大肠杆菌(E. Coli)
- 标记
- This Grancalcin protein is labelled with His tag.
- 应用范围
- SDS-PAGE (SDS)
- 产品特性
- GCA, 1-217aa, Human, His tag, E.coli
- 纯度
- > 95 % by SDS - PAGE
- Top Product
- Discover our top product GCA 蛋白
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- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1.0 mg/ml (determined by BCA assay)
- 缓冲液
- Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol 0.1M NaCl
- 储存条件
- 4 °C
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- 抗原
- Grancalcin (GCA) (Grancalcin, EF-Hand Calcium Binding Protein (GCA))
- 别名
- GCA (GCA 产品)
- 别名
- Grancalcin Protein, 5133401E04Rik Protein, AI573844 Protein, GCL Protein, zgc:92027 Protein, grancalcin Protein, Grancalcin Protein, zgc:92027 Protein, GCA Protein, gran Protein, LOC100280890 Protein, Gca Protein
- 背景
- GCA, also known as Grancalcin, is calcium-binding protein that is especially abundant in human neutrophils. It belongs to the penta EF-hand (PEF) subfamily of EF-hand proteins, which also comprises calpain, sorcin, peflin, and ALG-2. This protein undergoes important conformational changes upon binding of calcium, which subsequently exposes hydrophobic amino acid residues, which direct the protein to hydrophobic surfaces. It interacts with L-plastin, a protein known to have actin bundling activity, which suggests that GCA may play a role in the regulation of neutrophils adhesion. Recombinant human GCA protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: Grancalcin, GCL. NCBI no.: NP_036330
- 分子量
- 26.1 kDa (237aa), confirmed by MALDI-TOF
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