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Grancalcin Protein (GST tag)

GCA 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7318549
发货至: 中国
  • 抗原 See all Grancalcin (GCA) 蛋白
    Grancalcin (GCA) (Grancalcin, EF-Hand Calcium Binding Protein (GCA))
    蛋白类型
    Recombinant
    宿主
    • 8
    • 2
    资源
    • 7
    • 1
    • 1
    • 1
    大肠杆菌(E. Coli)
    标记
    This Grancalcin protein is labelled with GST tag.
    原理
    Recombinant Human Grancalcin/GCA Protein (GST Tag)
    序列
    Met 1-Ile217
    产品特性
    Recombinant Human Grancalcin is produced by our E.coli expression system and the target gene encoding Met1-Ile217 is expressed with a GST tag at the N-terminus.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product GCA 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from a 0.2 μm filtered solution of 20 mM TrisHCl, 500 mM Nacl, pH 8.5 .
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    Grancalcin (GCA) (Grancalcin, EF-Hand Calcium Binding Protein (GCA))
    别名
    Grancalcin/GCA (GCA 产品)
    别名
    Grancalcin Protein, 5133401E04Rik Protein, AI573844 Protein, GCL Protein, zgc:92027 Protein, grancalcin Protein, Grancalcin Protein, zgc:92027 Protein, GCA Protein, gran Protein, LOC100280890 Protein, Gca Protein
    背景

    Background: Grancalcin (GCA) is a member of the penta EF hand subfamily which includes sorcin, calpain and ALG2. Grancalcin is highly expressed bone marrow and also can detected in neutrophils and macrophages. Grancalcin interacts with L-plastin which known to have actin bundling activity. It indicates that Grancalcin may play an important role in the adhesion of neutrophils to fibronectin. Furthermore, Grancalcin localization is dependent upon calcium and magnesium. It associates with both the granule and membrane fractions, which suggested a role for grancalcin in granule-membrane fusion and degranulation.

    Synonym: Grancalcin, GCA, GCL

    分子量
    50.3 kDa
    UniProt
    P28676
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