Quick Overview for HRAS Protein (AA 1-186) (ABIN667768)
抗原
See all HRAS 蛋白蛋白类型
宿主
资源
应用范围
纯度
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产品特性
- AA 1-186
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序列
- MTEYKLVVVG AGGVGKSALT IQLIQNHFVD EYDPTIEDSY RKQVVIDGET CLLDILDTAG QEEYSAMRDQ YMRTGEGFLC VFAINNSKSF ADINLYREQI KRVKDSDDVP MVLVGNKCDL PTRTVDTKQA HELAKSYGIP FIETSAKTRQ GVEDAFYTLV REIRQYRMKK LNSSDDGTQG CMGLPC
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产品特性
- NRAS, 1-186aa, Human, E.coli
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纯化方法
- > 95% by SDS-PAGE
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HRas proto-oncogene, GTPase (HRAS) (AA 1-189) protein (GST tag)
HRAS 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
HRas proto-oncogene, GTPase (HRAS) (AA 80-179) protein (GST tag)HRAS 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
HRas proto-oncogene, GTPase (HRAS) (AA 1-185) protein (His tag)HRAS 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % SDS
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 20 mM Tris-HCl buffer ( pH 7.5) containing 100 mM NaCl, 10 % glycerol
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
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- HRAS (HRas proto-oncogene, GTPase (HRAS))
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别名
- N-RAS
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背景
- Neuroblastoma RAS viral (v-ras) oncogene homolog, also known as NRAS, is a member of the RAS gene family. NRAS is an oncogene encoding a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. The encoded protein, which has intrinsic GTPase activity, is activated to a GTP-bound form by a GTPase activating protein and inactivated to a GDP-bound form by a guanine nucleotide-exchange factor. Recombinant human NRAS was expressed in E. coli and purified by using conventional chromatography techniques.
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分子量
- 20.8 kDa (186aa) confirmed by MALDI-TOF
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NCBI登录号
- NP_002515
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途径
- p53 Pathway, MAPK Pathway, RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Hepatitis C, Autophagy, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, Regulation of long-term Neuronal Synaptic Plasticity, VEGF Signaling, BCR Signaling
抗原
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