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SNIP1 Protein (AA 258-396) (His tag)

SNIP1 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 90 % by SDS - PAGE SDS
产品编号 ABIN667459
发货至: 中国
  • 抗原 See all SNIP1 蛋白
    SNIP1 (Smad Nuclear Interacting Protein 1 (SNIP1))
    蛋白类型
    Recombinant
    产品特性
    AA 258-396
    宿主
    • 3
    • 1
    • 1
    资源
    • 2
    • 1
    • 1
    • 1
    大肠杆菌(E. Coli)
    标记
    This SNIP1 protein is labelled with His tag.
    应用范围
    SDS-PAGE (SDS)
    产品特性
    SNIP1, 258-396aa, Human, His tag, E.coli
    纯度
    > 90 % by SDS - PAGE
    Top Product
    Discover our top product SNIP1 蛋白
  • 限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1mg/ml (determined by Bradford assay)
    缓冲液
    Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 2mM DTT, 20% glycerol, 100mM NaCl
    储存条件
    4 °C
  • 抗原
    SNIP1 (Smad Nuclear Interacting Protein 1 (SNIP1))
    别名
    SNIP1 (SNIP1 产品)
    别名
    MGC75890 Protein, snip1a Protein, SNIP1 Protein, PMRED Protein, 2410133M08Rik Protein, Smad nuclear interacting protein 1 Protein, Smad nuclear interacting protein 1 S homeolog Protein, smad nuclear interacting protein 1 Protein, MYST/Esa1 associated factor 6 Protein, snip1 Protein, snip1.S Protein, SNIP1 Protein, CC1G_02914 Protein, PTRG_06240 Protein, MEAF6 Protein, Snip1 Protein
    背景
    SNIP1 is smad nuclear interacting protein contains a forkhead-associated (FHA) domain and acts as a nuclear inhibitor of CBP/p300. This protein is an inhibitor of the TGF-beta signal transduction pathway and to be important in suppressing transcriptional activation dependent on the co-activators CBP and p300. Inhibition of NF-kappa B activity is a function of the N-terminal domain of SNIP1 and involves competition of SNIP1 and the NF-kappa B subunit, RelA/p65, for binding to p300, similar to the mechanism of inhibition of Smad signaling by SNIP1. Recombinant human SNIP1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Smad nuclear interacting protein 1, FLJ12553, Splicing factor arginine/serine rich 4. NCBI no.: NP_078976
    分子量
    18.8kDa (160aa), confirmed by MALDI-TOF
    途径
    SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection
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