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B-Cell Linker Protein (BLNK) (AA 1-456) (His tag)

BLNK 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 90 % by SDS - PAGE SDS
产品编号 ABIN667353
发货至: 中国
  • 抗原 See all B-Cell Linker (BLNK) 蛋白
    B-Cell Linker (BLNK)
    蛋白类型
    Recombinant
    产品特性
    AA 1-456
    宿主
    • 7
    • 1
    • 1
    资源
    • 3
    • 2
    • 2
    • 1
    • 1
    大肠杆菌(E. Coli)
    标记
    This B-Cell Linker protein is labelled with His tag.
    应用范围
    SDS-PAGE (SDS)
    产品特性
    BLNK, 1-456aa, Human, His tag, E.coli
    纯度
    > 90 % by SDS - PAGE
    Top Product
    Discover our top product BLNK 蛋白
  • 限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1.0 mg/ml (determined by BCA assay)
    缓冲液
    Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 0.1M NaCl, 1mM DTT, 0.1mM PMSF
    储存条件
    4 °C
  • 抗原
    B-Cell Linker (BLNK)
    别名
    BLNK (BLNK 产品)
    别名
    BLNK Protein, blnk Protein, MGC147045 Protein, BASH Protein, Bca Protein, Ly-57 Protein, Ly57 Protein, Lyw-57 Protein, SLP-65 Protein, AGM4 Protein, BLNK-S Protein, LY57 Protein, SLP65 Protein, bca Protein, B-cell linker Protein, B cell linker Protein, BLNK Protein, blnk Protein, Blnk Protein
    背景
    BLNK, also known as B-cell linker, is essential for normal B-cell development. This protein has been shown to associate with the effector proteins GRB2, Vav, NCK and PLC gamma following activation of the B cell receptor. It is phosphorylated by the Syk tyrosine kinase, which in turn permits activation of downstream effector proteins including GRB2 and PLC gamma. Recombinant human BLNK protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: B-cell linker, BASH, BLNK-S, LY57, MGC111051, SLP-65, SLP65. NCBI no.: AAH18906
    分子量
    52.6 kDa (476aa), confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)
    途径
    BCR Signaling
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