QPRT Protein (AA 1-297) (His tag)
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- 抗原 See all QPRT 蛋白
- QPRT (Quinolinate Phosphoribosyltransferase (QPRT))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-297
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宿主
- 人
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资源
- 大肠杆菌(E. Coli)
- 标记
- This QPRT protein is labelled with His tag.
- 应用范围
- SDS-PAGE (SDS)
- 产品特性
- QPRT, 1-297aa, Human, His tag, E.coli
- 纯度
- > 95 % by SDS - PAGE
- Top Product
- Discover our top product QPRT 蛋白
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- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1mg/ml (determined by Bradford assay)
- 缓冲液
- Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol
- 储存条件
- 4 °C
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- 抗原
- QPRT (Quinolinate Phosphoribosyltransferase (QPRT))
- 别名
- QPRT (QPRT 产品)
- 别名
- ECK0108 Protein, JW0105 Protein, VF2184 Protein, QPRTase Protein, 2410027J01Rik Protein, AI647766 Protein, quinolinate phosphoribosyltransferase Protein, nicotinate-nucleotide pyrophosphorylase Protein, nicotinate-nucleotide diphosphorylase Protein, carboxylating Protein, ECs0113 Protein, nadC Protein, VP2522 Protein, STY0167 Protein, BJE04_RS13210 Protein, QPRT Protein, Qprt Protein
- 背景
- Quinolinate phosphoribosyltransferase, also known as QPRT, is a major enzyme in the catabolism of quinolinate. It is an intermediate in the tryptophannicotinamide adenine dinucleotide (NAD) pathway, leading to the production of nicotinic acid, carbon dioxide and pyrophosphate. Elevation of QPRT levels in the brain has been linked to the pathogenesis of neurodegenerative disorders such as epilepsy, Alzheimer's disease, and Huntington's disease. Recombinant human QPRT protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Nicotinate nucleotide pyrophosphorylase carboxylating, Quinolinate phosphoribosyltransferase , QPRTase, QAPRTase. NCBI no.: NP_055113
- 分子量
- 32.9 kDa (317aa), confirmed by MALDI-TOF
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