14-3-3 sigma/SFN Protein (AA 1-248)
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- 抗原 See all 14-3-3 sigma/SFN (SFN) 蛋白
- 14-3-3 sigma/SFN (SFN) (Stratifin (SFN))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-248
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 应用范围
- SDS-PAGE (SDS)
- 产品特性
- 14-3-3 sigma, 1-248aa, Human, E.coli
- 纯度
- > 95 % by SDS - PAGE
- Top Product
- Discover our top product SFN 蛋白
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Stratifin (SFN) (AA 1-248) protein (GST tag)
SFN 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Stratifin (SFN) (AA 3-238) protein (GST tag)SFN 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Stratifin (SFN) (AA 1-248) protein (Strep Tag)Crystallography grade SFN 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Stratifin (SFN) (AA 1-248), (full length) protein (GST tag)SFN 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % SDS
Stratifin (SFN) proteinSFN 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % WB, SDS, ELISA, IP
Stratifin (SFN) protein (Myc-DYKDDDDK Tag)SFN 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/ml (determined by Bradford assay)
- 缓冲液
- Liquid. In 20mM Tris-HCl buffer (pH8.0) containing 50mM NaCl, 10% glycerol
- 储存条件
- 4 °C
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- 抗原
- 14-3-3 sigma/SFN (SFN) (Stratifin (SFN))
- 别名
- 14-3-3 sigma (SFN 产品)
- 别名
- YWHAS Protein, Er Protein, Mme1 Protein, Ywhas Protein, stratifin Protein, SFN Protein, Sfn Protein
- 背景
- 14-3-3 sigma ,also known as Stratifin (SFN), belong to the 14-3-3 family. The 14-3-3 family of proteins plays a key regulatory role in signal transduction, checkpoint control, apoptotic and nutrient-sensing pathways. 14-3-3 proteins are highly conserved and ubiquitously expressed. There are at least seven isoforms, beta, gamma, epsilon, sigma, zeta, tau and eta that have been identified in mammals. 14-3-3 sigma was identified as an epithelial cell marker and appeared to function as a tumor suppressor whose expression can be down regulated via methylation. Loss of 14-3-3 sigma expression results in a defective G2/M phase checkpoint and appears to contribute to both epithelial and non-epithelial tumorigenesis. Recombinant human 14-3-3 sigma was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: stratifin, Epithelial cell marker protein 1, HME1, YWHAS, SFN, 14-3-3 sigma. NCBI no.: NP_006133
- 分子量
- 27.7 kDa (248aa), confirmed by MALDI-TOF.
- 途径
- p53 Pathway, Myometrial Relaxation and Contraction
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