TPMT Protein (AA 1-245)
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- 抗原 See all TPMT 蛋白
- TPMT (Thiopurine S-Methyltransferase (TPMT))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-245
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 应用范围
- SDS-PAGE (SDS)
- 产品特性
- TPMT, 1-245aa, Human, Recombinant, E.coli
- 纯度
- > 95 % by SDS - PAGE
- Top Product
- Discover our top product TPMT 蛋白
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Thiopurine S-Methyltransferase (TPMT) (AA 1-245) protein (GST tag)
TPMT 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP
Thiopurine S-Methyltransferase (TPMT) (AA 1-245) protein (Strep Tag)Crystallography grade TPMT 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, SDS, WB
Thiopurine S-Methyltransferase (TPMT) (AA 1-240) protein (Strep Tag)Crystallography grade TPMT 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, SDS, WB
Thiopurine S-Methyltransferase (TPMT) (AA 4-244), (partial) protein (GST tag)TPMT 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant 95 % ELISA
Thiopurine S-Methyltransferase (TPMT) protein (Myc-DYKDDDDK Tag)TPMT 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/ml (determined by Bradford assay)
- 缓冲液
- In 20mM Tris 8.0, 0.2mM PMSF, 2mM EDTA
- 储存条件
- 4 °C
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- 抗原
- TPMT (Thiopurine S-Methyltransferase (TPMT))
- 别名
- TPMT (TPMT 产品)
- 别名
- MGC84277 Protein, AW106912 Protein, NHLRC1 Protein, thiopurine S-methyltransferase L homeolog Protein, thiopurine S-methyltransferase, tandem duplicate 2 Protein, thiopurine S-methyltransferase TpmT Protein, thiopurine S-methyltransferase Protein, Thiopurine S-methyltransferase Protein, thiopurine methyltransferase Protein, tpmt.L Protein, tpmt.2 Protein, tpmT Protein, MCA0794 Protein, Pnap_4948 Protein, Hhal_1383 Protein, TK90_1044 Protein, Slit_1144 Protein, Tint_0842 Protein, Fbal_3334 Protein, Celly_3188 Protein, Weevi_1737 Protein, Psefu_2696 Protein, Metme_3860 Protein, Tpmt Protein, TPMT Protein
- 背景
- TPMT, thiopurine S-methyltransferase, is a cytosolic enzyme that metabolizes thiopurine drugs via S-adenosyl-L-methionine as the S-methyl donor and S-adenosyl-L-homocysteine as a byproduct. Thiopurine drugs such as 6-mercaptopurine and azathioprine are used as chemotherapeutic agents. TPMT activity exhibits autosomal codominant genetic polymorphism, and patients inheriting TPMT-deficiency are at high risk of potentially fatal hematopoietic toxicity. Recombinant human TPMT was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Thiopurine S-methyltransferase, TPMT, Thiopurine S-methyltransferase HGNC:12014, S adenosyl L methionine thiopurine S methyltransferase, Thiopurine methyltransferase, Thiopurine S methyltransferase. NCBI no.: AAH05339
- 分子量
- 28 kDa (245 aa), confirmed by MALDI-TOF.
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