CD94 Protein, CD94-B Protein, Cd94 Protein, killer cell lectin like receptor D1 Protein, killer cell lectin-like receptor subfamily D, member 1 Protein, killer cell lectin-like receptor, subfamily D, member 1 Protein, KLRD1 Protein, Klrd1 Protein
背景
KLRD1, also known as natural killer cells antigen CD94 isoform 1, is expressed on the surface of natural killer cells in the innate immune system. It plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. This protein can form disulfide-bonded heterodimer with NKG2 family members. CD94 and NKG2 complex interacts with Human Leukocyte Antigen (HLA)-E on target cells on the surface of natural killer cells. Recombinant human KLRD1, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
分子量
18.2kDa (157aa) 18-28kDa (SDS-PAGE under reducing conditions.)