FCAR Protein (AA 22-227) (His tag)
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- 抗原 See all FCAR 蛋白
- FCAR (Fc Fragment of IgA, Receptor For (FCAR))
- 蛋白类型
- Recombinant
- 产品特性
- AA 22-227
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宿主
- 人
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资源
- Baculovirus infected Insect Cells
- 标记
- This FCAR protein is labelled with His tag.
- 应用范围
- SDS-PAGE (SDS)
- 序列
- ADPQEGDFPM PFISAKSSPV IPLDGSVKIQ CQAIREAYLT QLMIIKNSTY REIGRRLKFW NETDPEFVID HMDANKAGRY QCQYRIGHYR FRYSDTLELV VTGLYGKPFL SADRGLVLMP GENISLTCSS AHIPFDRFSL AKEGELSLPQ HQSGEHPANF SLGPVDLNVS GIYRCYGWYN RSPYLWSFPS NALELVVTDS IHQDYTTQNH HHHHH
- 纯度
- > 85 % by SDS - PAGE
- 内毒素水平
- < 1.0 EU per 1ug of protein (determined by LAL method)
- Top Product
- Discover our top product FCAR 蛋白
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Fc Fragment of IgA, Receptor For (FCAR) protein (His tag)
FCAR 宿主: 人 宿主: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
Fc Fragment of IgA, Receptor For (FCAR) (AA 24-133) protein (GST tag)FCAR 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Fc Fragment of IgA, Receptor For (FCAR) protein (His tag)FCAR 宿主: 大鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.25 mg/mL
- 缓冲液
- Liquid. In Phosphate Buffered Saline ( pH 7.4) containing 10 % glycerol.
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- 抗原
- FCAR (Fc Fragment of IgA, Receptor For (FCAR))
- 别名
- FCAR (FCAR 产品)
- 别名
- CD89 Protein, Fc fragment of IgA receptor Protein, Fc fragment of IgA, receptor for Protein, FCAR Protein
- 背景
- FCAR, also known as immunoglobulin alpha Fc receptor isoform, is a member of the multichain immune recognition receptor family which is the most abundant immunoglobulin in mucosal areas but is only the second most common antibody isotype in serum. It plays a role in both pro- and anti-inflammatory responses depending on the state of IgA bound. It is also an important Fc receptor for neutrophil killing of tumor cells. When FCAR expressing neutrophils come into contact with IgA-opsonized tumor cells, the neutrophils not only perform antibody-dependent cell-mediated cytotoxicity, but also release the cytokines TNF-alpha and IL-1beta which cause increased neutrophil migration to the site. Recombinant human FCAR, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
- 分子量
- 24.5kDa (215aa) 28-40kDa (SDS-PAGE under reducing conditions)
- NCBI登录号
- NP_001991
- UniProt
- P24071
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