FCAR Protein (AA 22-227) (His tag)
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- 抗原 See all FCAR 蛋白
- FCAR (Fc Fragment of IgA, Receptor For (FCAR))
- 蛋白类型
- Recombinant
- 产品特性
- AA 22-227
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宿主
- 人
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资源
- 人细胞
- 标记
- This FCAR protein is labelled with His tag.
- 原理
- Recombinant Human Immunoglobulin α Fc Receptor/FCAR/CD89 (C-6His)
- 序列
- QEGDFPMPFI SAKSSPVIPL DGSVKIQCQA IREAYLTQLM IIKNSTYREI GRRLKFWNET DPEFVIDHMD ANKAGRYQCQ YRIGHYRFRY SDTLELVVTG LYGKPFLSAD RGLVLMPGEN ISLTCSSAHI PFDRFSLAKE GELSLPQHQS GEHPANFSLG PVDLNVSGIY RCYGWYNRSP YLWSFPSNAL ELVVTDSIHQ DYTTQNVDHH HHHH
- 产品特性
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Recombinant Human Immunoglobulin α Fc Receptor/FCAR/CD89 (C-6His)
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 过滤
- 0.2 μm filtered
- 内毒素水平
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product FCAR 蛋白
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Fc Fragment of IgA, Receptor For (FCAR) protein (His tag)
FCAR 宿主: 人 宿主: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
Fc Fragment of IgA, Receptor For (FCAR) (AA 24-133) protein (GST tag)FCAR 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Fc Fragment of IgA, Receptor For (FCAR) protein (His tag)FCAR 宿主: 大鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - 缓冲液
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.
- 注意事项
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- 储存条件
- 4 °C/-20 °C/-80 °C
- 储存方法
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Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- FCAR (Fc Fragment of IgA, Receptor For (FCAR))
- 别名
- Immunoglobulin alpha Fc Receptor/FCAR (FCAR 产品)
- 别名
- CD89 Protein, Fc fragment of IgA receptor Protein, Fc fragment of IgA, receptor for Protein, FCAR Protein
- 背景
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Recombinant Human Immunoglobulin α Fc Receptor/FCAR produced by transfected human cells is a secreted protein with sequence (Gln22-Asn227) of Human FCAR fused with a polyhistidine tag at the C-terminus.
Immunoglobulin α Fc Receptor (IgA Fc Receptor) is a member of the immunoglobulin gene superfamily. It is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils, where it mediates immunologic responses to pathogens through the charged arginin residue within its transmembrane domain. IgA Fc Receptor binds both IgA1 and IgA2 with similar affinity. The site of interaction between FCAR and IgA was identified in the first extracellular domain of FCAR and the C2/C3 junction of IgA. It interacts with IgA-opsonized targets and triggers several immunologic defense processes, including phagocytosis, antibody-dependent cell-mediated cytotoxicity, and stimulation of the release of inflammatory mediators. FCAR is also expressed on Kupffer cells in the liver, where it was suggested to provide a second line of defense. - 分子量
- 24.52 kDa
- UniProt
- P24071
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