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GFRA1 Protein (AA 25-430) (hIgG-His-tag)
GFRA1
宿主: 大鼠
宿主: Baculovirus infected Insect Cells
Recombinant
> 85 % by SDS - PAGE
SDS
产品细节
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抗原
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GFRA1
(GDNF Family Receptor alpha 1 (GFRA1))
蛋白类型
Recombinant
产品特性
AA 25-430
宿主
All origins for GFRA1 蛋白
大鼠
资源
All sources for GFRA1 蛋白
Baculovirus infected Insect Cells
标记
This GFRA1 protein is labelled with hIgG-His-tag.
应用范围
SDS-PAGE (SDS)
序列
DRLDCVKASD QCLKEQSCST KYRTLRQCVA GKETNFSLTS GLEAKDECRS AMEALKQKSL YNCRCKRGMK KEKNCLRIYW SMYQSLQGND LLEDSPYEPV NSRLSDIFRA VPFISDVFQQ VEHISKGNNC LDAAKACNLD DTCKKYRSAY ITPCTTSMSN EVCNRRKCHK ALRQFFDKVP AKHSYGMLFC SCRDIACTER RRQTIVPVCS YEERERPNCL SLQDSCKTNY ICRSRLADFF TNCQPESRSV SNCLKENYAD CLLAYSGLIG TVMTPNYVDS SSLSVAPWCD CSNSGNDLED CLKFLNFFKD NTCLKNAIQA FGNGSDVTMW QPAPPVQTTT ATTTTAFRVK NKPLGPAGSE NEIPTHVLPP CANLQAQKLK SNVSGSTHLC LSDSDFGKDG LAGASSLEPK SCDKTHTCPP CPAPELLGGP SVFLFPPKPK DTLMISRTPE VTCVVVDVSH EDPEVKFNWY VDGVEVHNAK TKPREEQYNS TYRVVSVLTV LHQDWLNGKE YKCKVSNKAL PAPIEKTISK AKGQPREPQV YTLPPSRDEL TKNQVSLTCL VKGFYPSDIA VEWESNGQPE NNYKTTPPVL DSDGSFFLYS KLTVDKSRWQ QGNVFSCSVM HEALHNHYTQ KSLSLSPGKH HHHHH
纯度
> 85 % by SDS - PAGE
内毒素水平
< 1.0 EU per 1 microgram of protein (determined by LAL method)
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使用细节
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应用备注
Optimal working dilution should be determined by the investigator.
限制
仅限研究用
贮存及处理
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状态
Liquid
浓度
0.25 mg/mL
缓冲液
Liquid. In Phosphate Buffered Saline ( pH 7.4) containing 10 % glycerol.
储存条件
4 °C,-20 °C,-80 °C
储存方法
Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
目标详细情况
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抗原
GFRA1
(GDNF Family Receptor alpha 1 (GFRA1))
别名
Gfra1 (GFRA1 产品 )
别名
gdnfr Protein, ret1l Protein, retl1 Protein, trnr1 Protein, gdnfra Protein, MGC122616 Protein, gfr-alpha-1 Protein, GDNFR Protein, GDNFRA Protein, GFR-ALPHA-1 Protein, RET1L Protein, RETL1 Protein, TRNR1 Protein, GDNFRALPHA Protein, GFRA1 Protein, AU042498 Protein, gfralpha1a Protein, zgc:110129 Protein, GDNF family receptor alpha 1 Protein, glial cell line derived neurotrophic factor family receptor alpha 1 Protein, gdnf family receptor alpha 1a Protein, gfra1 Protein, GFRA1 Protein, Gfra1 Protein, gfra1a Protein
背景
Gfra1, also known as GDNF family receptor alpha-1, is a member of the GDNF receptor family. It is a glycosyl-phosphatidylinositol(GPI)-linked cell surface receptor for both Glial cell line-derived growth factor (GDNF), neurturin (NTN), and mediates activation of the RET tyrosine kinase receptor. This protein is a potent survival factor for central and peripheral neurons, and is essential for the development of kidneys and the enteric nervous system. Recombinant rat Gfra1 protein, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
分子量
72.3kDa (645aa) 70-100KDa (SDS-PAGE under reducing conditions.)
NCBI登录号
NP_037091
UniProt
Q62997
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GFRA1 蛋白
GFRA1 Protein (AA 25-430) (hIgG-His-tag) (ABIN6388021)