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CST3 Protein (AA 21-140) (His tag)

CST3 宿主: 小鼠 宿主: Baculovirus infected Insect Cells Recombinant > 95 % by SDS - PAGE SDS Active
产品编号 ABIN5777481
发货至: 中国
  • 抗原 See all CST3 蛋白
    CST3 (Cystatin C (CST3))
    蛋白类型
    Recombinant
    生物活性
    Active
    产品特性
    AA 21-140
    宿主
    • 16
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    小鼠
    资源
    • 16
    • 6
    • 4
    • 4
    • 2
    • 2
    • 2
    Baculovirus infected Insect Cells
    标记
    This CST3 protein is labelled with His tag.
    应用范围
    SDS-PAGE (SDS)
    序列
    ATPKQGPRML GAPEEADANE EGVRRALDFA VSEYNKGSND AYHSRAIQVV RARKQLVAGV NYFLDVEMGR TTCTKSQTNL TDCPFHDQPH LMRKALCSFQ IYSVPWKGTH SLTKFSCKNA HHHHHH
    纯度
    > 95 % by SDS - PAGE
    内毒素水平
    < 1.0 EU per 1 microgram of protein (determined by LAL method)
    Biological Activity Comment
    The IC50 value is < 1.0nM. The inhibitory function of Cystatin 3 on protease activity of papain was measured by a fluorometric assay using Z-FR-AMC at pH 7.5 at 25C
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    Discover our top product CST3 蛋白
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    说明

    Bioactivity Validated

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Liquid. In Phosphate Buffered Saline (  pH 7.4) containing 10 % glycerol.
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
  • 抗原
    CST3 (Cystatin C (CST3))
    别名
    Cystatin-C (CST3 产品)
    别名
    armd11 Protein, fb51d07 Protein, wu:fb24g06 Protein, wu:fb51d07 Protein, wu:fc55f03 Protein, zgc:136227 Protein, ARMD11 Protein, CysC Protein, CYSC Protein, cystatin C Protein, cystatin C L homeolog Protein, cystatin C (amyloid angiopathy and cerebral hemorrhage) Protein, cystatin 3 Protein, CST3 Protein, cst3.L Protein, cst3 Protein, cystatin 3 Protein, Cst3 Protein
    背景
    CST3, also known as Cystatin-C is a member of family 2 of the cystatin superfamily. This protein is a secreted type 2 cysteine protease inhibitor synthesized in all nucleated cells, has been proposed as a replacement for serum creatinine for the assessment of renal function, particularly to detect small reductions in glomerular filtration rate. It is involved in processes such as tumor invasion and metastasis, inflammation and some neurological diseases. It inhibits many cysteine proteases such as papain and cathepsins B, H, K, L and S. It indicates that a murine model should be relevant for studies of the human disease, hereditary Cystatin C amyloid angiopathy. Recombinant Mouse CST3, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
    分子量
    14.2kDa (126aa) confirmed by MALDI-TOF 13.5-18KDa (SDS-PAGE under reducing conditions.)
    NCBI登录号
    NP_034106
    UniProt
    P21460
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