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Galectin 3 Protein (LGALS3) (AA 1-264) (His tag)

LGALS3 宿主: 小鼠 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % by SDS - PAGE SDS Active
产品编号 ABIN7281081
发货至: 中国
  • 抗原 See all Galectin 3 (LGALS3) 蛋白
    Galectin 3 (LGALS3)
    蛋白类型
    Recombinant
    生物活性
    Active
    产品特性
    AA 1-264
    宿主
    • 17
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    小鼠
    资源
    • 18
    • 6
    • 4
    • 2
    • 1
    • 1
    大肠杆菌(E. Coli)
    标记
    This Galectin 3 protein is labelled with His tag.
    应用范围
    SDS-PAGE (SDS)
    序列
    MGSSHHHHHH SSGLVPRGSH MGSMADSFSL NDALAGSGNP NPQGYPGAWG NQPGAGGYPG AAYPGAYPGQ APPGAYPGQA PPGAYPGQAP PSAYPGPTAP GAYPGPTAPG AYPGSTAPGA FPGQPGAPGA YPSAPGGYPA AGPYGVPAGP LTVPYDLPLP GGVMPRMLIT IMGTVKPNAN RIVLDFRRGN DVAFHFNPRF NENNRRVIVC NTKQDNNWGK EERQSAFPFE SGKPFKIQVL VEADHFKVAV NDAHLLQYNH RMKNLREISQ LGISGDITLT SANHAMI
    纯度
    > 95 % by SDS - PAGE
    Biological Activity Comment
    The ED50 for this effect is equal or higher than 25 ug/ml. Measured by its ability to agglutinate human red blood cells.
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    Discover our top product LGALS3 蛋白
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    说明

    Bioactivity Validated

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.5 mg/mL
    缓冲液
    Liquid. In 20  mM Tris-HCl buffer (  pH 8.0) containing 0.15M NaCl, 50 % glycerol,1  mM DTT, 2  mM EDTA
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
  • 抗原
    Galectin 3 (LGALS3)
    别名
    LGALS3 (LGALS3 产品)
    别名
    CBP 35 Protein, Gal-3 Protein, Galectin-3 Protein, leg3 Protein, galactoside-binding Protein, galectin-3 Protein, lectin Protein, soluble Protein, CBP35 Protein, GAL3 Protein, GALBP Protein, GALIG Protein, L31 Protein, LGALS2 Protein, MAC2 Protein, MGC52947 Protein, MGC75803 Protein, LGALS3 Protein, gal-3 Protein, GBP Protein, L-34 Protein, Mac-2 Protein, gal3 Protein, galectin 3 Protein, Galectin-3 Protein, avian beta-defensin 3 Protein, lectin, galactoside-binding, soluble, 3 L homeolog Protein, lectin, galactoside-binding, soluble, 3 Protein, galectin 2 Protein, lectin, galactose binding, soluble 3 Protein, LGALS3 Protein, leg3 Protein, AvBD3 Protein, lgals3.L Protein, lgals3 Protein, LGALS2 Protein, Lgals3 Protein
    物质类
    Chemical
    背景
    LGALS3, also known as galectin 3, is a member of the family of animal lectins, which selectively binds beta-galactoside residues. This protein is secreted from cells by ectocytosis, which is independent of the classical secretory pathway through the endoplasmic reticulum/Golgi network. LGALS3 has been associated with the inhibition of apoptosis and the progression of cancer. It is normally distributed in epithelia of many organs, in various inflammatory cells, including macrophages, as well as dendritic cells and Kupffer cells. The expression of this lectin is up-regulated during inflammation, cell proliferation, cell differentiation and through trans-activation by viral proteins. Recombinant mouse LGALS3 protein, used to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
    分子量
    29.8 kDa (287aa) confirmed by MALDI-TOF
    NCBI登录号
    NP_034835
    途径
    RTK signaling
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