DUSP6 Protein (AA 1-381) (His tag)
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- 抗原 See all DUSP6 蛋白
- DUSP6 (Dual Specificity Phosphatase 6 (DUSP6))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-381
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This DUSP6 protein is labelled with His tag.
- 应用范围
- SDS-PAGE (SDS)
- 序列
- MGSSHHHHHH SSGLVPRGSH MIDTLRPVPF ASEMAISKTV AWLNEQLELG NERLLLMDCR PQELYESSHI ESAINVAIPG IMLRRLQKGN LPVRALFTRG EDRDRFTRRC GTDTVVLYDE SSSDWNENTG GESVLGLLLK KLKDEGCRAF YLEGGFSKFQ AEFSLHCETN LDGSCSSSSP PLPVLGLGGL RISSDSSSDI ESDLDRDPNS ATDSDGSPLS NSQPSFPVEI LPFLYLGCAK DSTNLDVLEE FGIKYILNVT PNLPNLFENA GEFKYKQIPI SDHWSQNLSQ FFPEAISFID EARGKNCGVL VHCLAGISRS VTVTVAYLMQ KLNLSMNDAY DIVKMKKSNI SPNFNFMGQL LDFERTLGLS SPCDNRVPAQ QLYFTTPSNQ NVYQVDSLQS T
- 纯度
- > 85 % by SDS - PAGE
- Top Product
- Discover our top product DUSP6 蛋白
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Dual Specificity Phosphatase 6 (DUSP6) (AA 1-381) protein (His tag)
DUSP6 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Dual Specificity Phosphatase 6 (DUSP6) (AA 1-381) protein (GST tag)DUSP6 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Dual Specificity Phosphatase 6 (DUSP6) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)DUSP6 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.25 mg/mL
- 缓冲液
- Liquid. In 20 mM Tris-HCl buffer ( pH 8.0) containing 0.15M NaCl, 10 % glycerol, 1 mM DTT
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- 抗原
- DUSP6 (Dual Specificity Phosphatase 6 (DUSP6))
- 别名
- DuSP6 (DUSP6 产品)
- 别名
- HH19 Protein, MKP3 Protein, PYST1 Protein, 1300019I03Rik Protein, MKP-3 Protein, Mkp3 Protein, wu:fd99d09 Protein, mkp3 Protein, pyst1 Protein, DUSP6 Protein, dusp6 Protein, dual specificity phosphatase 6 Protein, dual specificity phosphatase 6 L homeolog Protein, Dual specificity protein phosphatase 6 Protein, DUSP6 Protein, Dusp6 Protein, dusp6 Protein, dusp6.L Protein, dus6 Protein
- 背景
- DuSP6 is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. Recombinant human DuSP6 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- 分子量
- 44.4 kDa (401aa) confirmed by MALDI-TOF
- NCBI登录号
- NP_001937
- UniProt
- Q16828
- 途径
- Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades
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