CD33 Protein (CD33) (AA 18-259) (Fc Tag)
-
- 抗原 See all CD33 蛋白
- CD33
- 蛋白类型
- Recombinant
- 生物活性
- Active
- 产品特性
- AA 18-259
-
宿主
- 人
-
资源
- HEK-293 Cells
- 标记
- This CD33 protein is labelled with Fc Tag.
- 序列
- AA 18-259
- 纯度
- >95 % as determined by SDS-PAGE.
- 内毒素水平
- Less than 0.01 EU per μg by the LAL method.
- Top Product
- Discover our top product CD33 蛋白
-
-
- 限制
- 仅限研究用
-
- 状态
- Lyophilized
- 缓冲液
- Tris with Glycine, Arginine and NaCl, pH 7.5
- 注意事项
- Please avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
-
- 抗原
- CD33
- 别名
- Siglec-3 (CD33 产品)
- 别名
- SIGLEC-3 Protein, SIGLEC3 Protein, p67 Protein, Siglec-3 Protein, gp67 Protein, CD33 molecule Protein, CD33 antigen Protein, CD33 Protein, Cd33 Protein
- 背景
- Myeloid cell surface antigen CD33 is also known as SIGLEC3, Siglecs (sialic acid binding Ig-like lectins) and GP67, is a single-pass type I membrane protein which belongs to the immunoglobulin superfamily and SIGLEC (sialic acid binding Ig-like lectin) family. Human CD33 / Siglec-3 cDNA encodes a 364 amino acid (aa) polypeptide with a hydrophobic signal peptide, an N--terminal Ig--like V--type domain, one Ig--like C2--type domains, a transmembrane region and a cytoplasmic tail. CD33 / Siglec-3 usually considered myeloid-specific, but it can also be found on some lymphoid cells. In the immune response, CD33 / Siglec-3 may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. CD33 / Siglec-3 induces apoptosis in acute myeloid leukemia.
- 分子量
- 54.6 kDa
-