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CD33 Protein (CD33) (AA 18-259) (His-Avi Tag)

CD33 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
产品编号 ABIN7274159
发货至: 中国
  • 抗原 See all CD33 蛋白
    CD33
    蛋白类型
    Recombinant
    产品特性
    AA 18-259
    宿主
    • 35
    • 7
    • 1
    • 1
    资源
    • 29
    • 6
    • 3
    • 3
    • 2
    • 1
    HEK-293 Cells
    标记
    This CD33 protein is labelled with His-Avi Tag.
    原理
    Human Siglec-3/CD33 Protein
    序列
    Asp18-His259
    产品特性
    Recombinant Human Siglec-3/CD33 Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Asp18-His259.
    纯度
    > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
    过滤
    0.22 μm filtered
    内毒素水平
    Less than 1EU per μg by the LAL method.
    Biological Activity Comment
    Immobilized Human Siglec-3, His Tag at 0.5μg/ml (100μl/Well) on the plate. Dose response curve for Anti-Siglec-3 Antibody, hFc Tag with the EC50 of 5.1ng/ml determined by ELISA. See testing image for detail.
  • 限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Supplied as 0.22μm filtered solution in 20 mM PB, 500 mM NaCl ( pH 8.0).
    储存条件
    -80 °C
    储存方法
    Valid for 12 months from date of receipt when stored at -80°C., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    CD33
    别名
    Siglec-3 (CD33 产品)
    别名
    SIGLEC-3 Protein, SIGLEC3 Protein, p67 Protein, Siglec-3 Protein, gp67 Protein, CD33 molecule Protein, CD33 antigen Protein, CD33 Protein, Cd33 Protein
    背景
    Sialic-acid-binding immunoglobulin-like lectin (Siglec) that plays a role in mediating cell-cell interactions and in maintaining immune cells in a resting state.They are sialoadhesin/CD169/Siglec-1, CD22/Siglec-2, CD33/Siglec-3, Myelin-Associated Glycoprotein (MAG/Siglec-4a) and Siglecs 5 to 11. To date, no Siglec has been shown to recognized any cell surface ligand other than sialic acids, suggesting that interactions with glycans containing this carbohydrate are important in mediating the biological functions of Siglecs.
    分子量
    29.6 kDa. Due to glycosylation, the protein migrates to 52-60 kDa based on Tris-Bis PAGE result.
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