ICOS Protein (AA 21-139) (Fc Tag)
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- 抗原 See all ICOS 蛋白
- ICOS (Inducible T-Cell Co-Stimulator (ICOS))
- 蛋白类型
- Recombinant
- 产品特性
- AA 21-139
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宿主
- 人
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资源
- CHO Cells
- 标记
- This ICOS protein is labelled with Fc Tag.
- 原理
- CD278 [ICOS] (human):Fc (human) (rec.)
- 特异性
- The extracellular domain of human CD278 [ICOS] (aa 21-139) is fused to the N-terminus of the Fc region of human IgG1.
- 产品特性
- Protein. The extracellular domain of human CD278 [ICOS] (aa 21-139) is fused to the N-terminus of the Fc region of human IgG1. Source: CHO cells. Endotoxin content: <0.06EU/μg protein (LAL test, Lonza). Lyophilized from 0.2μm-filtered solution in PBS. Purity: >98 % (SDS-PAGE). CD278, also called inducible costimulator (ICOS) or CRP1 (CD28-related protein-1), is a member of the growing CD28 family of immune costimulatory receptors. Other family members are CD28, CTLA-4 and PD-1. ICOS is expressed on most CD45RO+ cells. ICOS expression is upregulated within approximately 24-48 hours of activation on Th primed cells. B7-H2, a member of the B7 family of costimulatory ligands, has been identified as the ICOS ligand. The B7-H2/ICOS interaction appears to play roles in T cell dependent B cell activation and Th differentiation.
- 纯度
- >98 % (SDS-PAGE)
- 内毒素水平
- <0.06EU/μg protein (LAL test, Lonza).
- Top Product
- Discover our top product ICOS 蛋白
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Inducible T-Cell Co-Stimulator (ICOS) (AA 21-144) protein (Fc Tag)
ICOS 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Inducible T-Cell Co-Stimulator (ICOS) (AA 21-141) protein (Fc Tag)ICOS 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Inducible T-Cell Co-Stimulator (ICOS) (AA 21-134) protein (His tag)ICOS 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Inducible T-Cell Co-Stimulator (ICOS) (Cys136Ser-Mutant), (Cys137Ser-Mutant) protein (His tag)ICOS 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Inducible T-Cell Co-Stimulator (ICOS) (Cys137Ser-Mutant), (Cys138Ser-Mutant) protein (His tag)ICOS 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Inducible T-Cell Co-Stimulator (ICOS) protein (Fc Tag)ICOS 宿主: 猕猴 宿主: 人细胞 Recombinant > 90 % as determined by reducing SDS-PAGE.
Inducible T-Cell Co-Stimulator (ICOS) (AA 1-168) protein (GST tag)ICOS 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Inducible T-Cell Co-Stimulator (ICOS) (AA 21-140) protein (GST tag)ICOS 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Inducible T-Cell Co-Stimulator (ICOS) protein (mFc-His Tag)ICOS 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. ELISA
Inducible T-Cell Co-Stimulator (ICOS) protein (Fc Tag)ICOS 宿主: 大鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 浓度
- Lot specific
- 缓冲液
- Lyophilized from 0.2μm-filtered solution in PBS.
- 注意事项
- Avoid freeze/thaw cycles.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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Short Term Storage: +4°C
Long Term Storage: -20°C
Use & Stability: Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
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- 抗原
- ICOS (Inducible T-Cell Co-Stimulator (ICOS))
- 别名
- CD278 [ICOS] (ICOS 产品)
- 别名
- ICOS Protein, AILIM Protein, CCLP Protein, CRP-1 Protein, H4 Protein, Ly115 Protein, CD278 Protein, CVID1 Protein, Ailim Protein, inducible T-cell costimulator Protein, inducible T cell co-stimulator Protein, inducible T-cell co-stimulator Protein, ICOS Protein, LOC100232284 Protein, Icos Protein
- 背景
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Alternate Names/Synonyms: ICOS, Inducible T Cell Costimulator, CRP1, CD28-related Protein-1, AILIM
Product Description: CD278, also called inducible costimulator (ICOS) or CRP1 (CD28-related protein-1), is a member of the growing CD28 family of immune costimulatory receptors. Other family members are CD28, CTLA-4 and PD-1. ICOS is expressed on most CD45RO+ cells. ICOS expression is upregulated within approximately 24-48 hours of activation on Th primed cells. B7-H2, a member of the B7 family of costimulatory ligands, has been identified as the ICOS ligand. The B7-H2/ICOS interaction appears to play roles in T cell dependent B cell activation and Th differentiation.
- NCBI登录号
- NP_036224
- 途径
- Cancer Immune Checkpoints
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