IL-24 Protein (AA 53-207) (Fc Tag)
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- 抗原 See all IL-24 (IL24) 蛋白
- IL-24 (IL24) (Interleukin 24 (IL24))
- 蛋白类型
- Recombinant
- 产品特性
- AA 53-207
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宿主
- 人
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资源
- CHO Cells
- 标记
- This IL-24 protein is labelled with Fc Tag.
- 原理
- IL-24 (human):Fc (human) (rec.)
- 特异性
- The extracellular domain of human IL-24 (aa 53-207) is fused to the N-terminus of the Fc region of a human IgG1.
- 产品特性
- Protein. The extracellular domain of human IL-24 (aa 53-207) is fused to the N-terminus of the Fc region of a human IgG1. Source: CHO cells. Endotoxin content: <0.06EU/μg protein (LAL test, Lonza). Lyophilized from 0.2μm-filtered solution in PBS. Purity: >98 % (SDS-PAGE). IL-24 is a cytokine belonging to the IL-10 family of cytokines that signals through two heterodimeric receptors: IL-20R1/IL-20R2 and IL-22R1/IL-20R2. This interleukin is also known as melanoma differentiation-associated 7 (mda-7) due to its discovery as a tumour suppressing protein. IL-24 appears to control cell survival and proliferation by inducing rapid activation of particular transcription factors called STAT1 and STAT3. It is predominantly released by activated monocytes, macrophages and T helper 2 (Th2) cells and acts on non-haematopoietic tissues such as skin, lung and reproductive tissues. IL-24 performs important roles in wound healing, psoriasis and cancer. IL-24 has antiproliferative properties is inhibiting angiogenesis and may contribute to terminal cell differentiation.
- 纯度
- >98 % (SDS-PAGE)
- 内毒素水平
- <0.06EU/μg protein (LAL test, Lonza).
- Top Product
- Discover our top product IL24 蛋白
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Interleukin 24 (IL24) (AA 51-206) (Active) protein (His tag)
IL24 宿主: 人 宿主: 大肠杆菌（E. Coli） > 90 % AcA, CC Active
Interleukin 24 (IL24) (AA 1-207) protein (GST tag)IL24 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Interleukin 24 (IL24) (AA 1-206) protein (GST tag)IL24 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Interleukin 24 (IL24) (AA 58-167) protein (GST tag)IL24 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Interleukin 24 (IL24) (AA 52-206) protein (His tag)Crystallography grade IL24 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Interleukin 24 (IL24) (AA 27-181) protein (His tag)Crystallography grade IL24 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 浓度
- Lot specific
- 缓冲液
- Lyophilized from 0.2μm-filtered solution in PBS.
- 注意事项
- Avoid freeze/thaw cycles.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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Short Term Storage: +4°C
Long Term Storage: -20°C
Use & Stability: Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
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- 抗原
- IL-24 (IL24) (Interleukin 24 (IL24))
- 别名
- IL-24 (IL24 产品)
- 别名
- C49A Protein, FISP Protein, IL10B Protein, MDA7 Protein, MOB5 Protein, ST16 Protein, Mda7 Protein, St16 Protein, Mda-7 Protein, IL24 Protein, interleukin 24 Protein, IL24 Protein, Il24 Protein
- 背景
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Alternate Names/Synonyms: Interleukin-24, MDA7, ST16
Product Description: IL-24 is a cytokine belonging to the IL-10 family of cytokines that signals through two heterodimeric receptors: IL-20R1/IL-20R2 and IL-22R1/IL-20R2. This interleukin is also known as melanoma differentiation-associated 7 (mda-7) due to its discovery as a tumour suppressing protein. IL-24 appears to control cell survival and proliferation by inducing rapid activation of particular transcription factors called STAT1 and STAT3. It is predominantly released by activated monocytes, macrophages and T helper 2 (Th2) cells and acts on non-haematopoietic tissues such as skin, lung and reproductive tissues. IL-24 performs important roles in wound healing, psoriasis and cancer. IL-24 has antiproliferative properties is inhibiting angiogenesis and may contribute to terminal cell differentiation.
- 途径
- Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity, Autophagy
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