KAP1 Protein (AA 22-291, partial) (GST tag)
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- 抗原 See all KAP1 (TRIM28) 蛋白
- KAP1 (TRIM28) (Tripartite Motif Containing 28 (TRIM28))
- 蛋白类型
- Recombinant
- 产品特性
- AA 22-291, partial
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This KAP1 protein is labelled with GST tag.
- 应用范围
- SDS-PAGE (SDS), Western Blotting (WB), ELISA, Particle-Enhanced Turbidimetric Assay (PETIA)
- 序列
- PGEGSAGGEK RSTAPSAAAS ASASAAASSP AGGGAEALEL LEHCGVCRER LRPEREPRLL PCLHSACSAC LGPAAPAAAN SSGDGGAAGD GTVVDCPVCK QQCFSKDIVE NYFMRDSGSK AATDAQDANQ CCTSCEDNAP ATSYCVECSE PLCETCVEAH QRVKYTKDHT VRSTGPAKSR DGERTVYCNV HKHEPLVLFC ESCDTLTCRD CQLNAHKDHQ YQFLEDAVRN QRKLLASLVK RLGDKHATLQ KSTKEVRSSI RQVSDVQKRV
- 纯度
- 90 %
- Top Product
- Discover our top product TRIM28 蛋白
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Tripartite Motif Containing 28 (TRIM28) (AA 1-835) protein (GST tag)
TRIM28 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Tripartite Motif Containing 28 (TRIM28) (AA 379-524) protein (GST tag)TRIM28 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Tripartite Motif Containing 28 (TRIM28) (AA 2-835) protein (His tag)Crystallography grade TRIM28 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Tripartite Motif Containing 28 (TRIM28) (AA 2-834) protein (His tag)Crystallography grade TRIM28 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Tripartite Motif Containing 28 (TRIM28) (AA 624-811) protein (His tag,DYKDDDDK Tag)TRIM28 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Bind, ScA
Tripartite Motif Containing 28 (TRIM28) (AA 366-802) protein (His tag)TRIM28 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % by SDS - PAGE SDS
Tripartite Motif Containing 28 (TRIM28) protein (Myc-DYKDDDDK Tag)TRIM28 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- PBS buffer, 20mM GSH
- 储存条件
- 4 °C
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- 抗原
- KAP1 (TRIM28) (Tripartite Motif Containing 28 (TRIM28))
- 别名
- Transcription intermediary factor 1-beta (TRIM28 产品)
- 别名
- KAP1 Protein, RNF96 Protein, TF1B Protein, TIF1B Protein, TRIM28 Protein, kap1 Protein, rnf96 Protein, tf1b Protein, tif1b Protein, AA408787 Protein, KAP-1 Protein, KRIP-1 Protein, Tif1b Protein, Tif1beta Protein, Kap1 Protein, Krip1 Protein, TIF1BETA Protein, tripartite motif containing 28 Protein, tripartite motif containing 28 L homeolog Protein, tripartite motif-containing 28 Protein, TRIM28 Protein, trim28.L Protein, Trim28 Protein
- 背景
- Background: Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at 'Lys-9' (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 'Lys-9 and 'Lys-14' acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression. Recruitment of SETDB1 induces heterochromatinization. May play a role as a coactivator for CEBPB and NR3C1 in the transcriptional activation of ORM1. Also corepressor for ERBB4. Inhibits E2F1 activity by stimulating E2F1-HDAC1 complex formation and inhibiting E2F1 acetylation. May serve as a partial backup to prevent E2F1-mediated apoptosis in the absence of RB1. Important regulator of CDKN1A/p21(CIP1). Has E3 SUMO-protein ligase activity toward itself via its PHD-type zinc finger. Synonyms: E3 SUMO-protein ligase TRIM28 EC=6.3.2.- KRAB-associated protein 1 Short name=KAP-1 KRAB-interacting protein 1 Short name=KRIP-1 Nuclear corepressor KAP-1 RING finger protein 96 Tripartite motif-containing protein 28.
- 分子量
- 56.1 kD
- NCBI登录号
- NM_005762
- UniProt
- Q13263
- 途径
- Hedgehog Signaling, Positive Regulation of Response to DNA Damage Stimulus
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