RAD23A Protein (AA 2-201, partial) (GST tag)
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- 抗原 See all RAD23A 蛋白
- RAD23A (RAD23 Homolog A (RAD23A))
- 蛋白类型
- Recombinant
- 产品特性
- AA 2-201, partial
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宿主
- 人
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资源
- 大肠杆菌(E. Coli)
- 标记
- This RAD23A protein is labelled with GST tag.
- 应用范围
- SDS-PAGE (SDS), ELISA, Western Blotting (WB)
- 序列
- AVTITLKTLQ QQTFKIRMEP DETVKVLKEK IEAEKGRDAF PVAGQKLIYA GKILSDDVPI RDYRIDEKNF VVVMVTKTKA GQGTSAPPEA SPTAAPESST SFPPAPTSGM SHPPPAARED KSPSEESAPT TSPESVSGSV PSSGSSGREE DAASTLVTGS EYETMLTEIM SMGYERERVV AALRASYNNP HRAVEYLLTG
- 纯度
- 95 %
- Top Product
- Discover our top product RAD23A 蛋白
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- PBS buffer, 20mM GSH
- 储存条件
- 4 °C
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- 抗原
- RAD23A (RAD23 Homolog A (RAD23A))
- 别名
- UV excision repair protein RAD23 homolog A (RAD23A 产品)
- 别名
- rad23a Protein, wu:fe11h06 Protein, zgc:92001 Protein, RAD23A Protein, HHR23A Protein, HR23A Protein, 2310040P19Rik Protein, AL024030 Protein, mHR23A Protein, RAD23 homolog A, nucleotide excision repair protein a Protein, RAD23 homolog A, nucleotide excision repair protein Protein, rad23aa Protein, RAD23A Protein, Rad23a Protein
- 背景
- Background: Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Binds to 'Lys-48'-linked polyubiquitin chains in a length-dependent manner and with a lower affinity to 'Lys-63'-linked polyubiquitin chains. Proposed to be capable to bind simultaneously to the 26S proteasome and to polyubiquitinated substrates and to deliver ubiquitinated proteins to the proteasome. Ref.6 Ref.9 Ref.10 Ref.11 Ref.20 Involved in nucleotide excision repair and is thought to be functional equivalent for RAD23B in global genome nucleotide excision repair (GG-NER) by association with XPC. In vitro, the XPC:RAD23A dimer has NER activity. Can stabilize XPC. Ref.6 Ref.9 Ref.10 Ref.11 Ref.20 Involved in vpr-dependent replication of HIV-1 in non-proliferating cells and primary macrophages. Required for the association of HIV-1 vpr with the host proteasome. Synonyms: Short name=HR23A Short name=hHR23A
- 分子量
- 48.8 kD
- NCBI登录号
- NM_005053
- UniProt
- P54725
- 途径
- DNA Damage Repair
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