CD8B Protein (AA 22-170) (His tag)
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- 抗原 See all CD8B 蛋白
- CD8B (CD8b Molecule (CD8B))
- 蛋白类型
- Recombinant
- 产品特性
- AA 22-170
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宿主
- 人
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资源
- Baculovirus infected Insect Cells
- 标记
- This CD8B protein is labelled with His tag.
- 应用范围
- SDS-PAGE (SDS)
- 序列
- ADPFSAPKDQ QVVTAVEYQE AILACKTPKK TVSSRLEWKK LGRSVSFVYY QQTLQGDFKN RAEMIDFNIR IKNVTRSDAG KYRCEVSAPS EQGQNLEEDT VTLEVLVAPA VPSCEVPSSA LSGTVVELRC QDKEGNPAPE YTWFKDGIRL LENPRLGSQS TNSSYTMNTK TGTLQFNTVS KLDTGEYSCE ARNSVGYRRC PGKRMQVDDL NISLEPKSCD KTHTCPPCPA PELLGGPSVF LFPPKPKDTL MISRTPEVTC VVVDVSHEDP EVKFNWYVDG VEVHNAKTKP REEQYNSTYR VVSVLTVLHQ DWLNGKEYKC KVSNKALPAP IEKTISKAKG QPREPQVYTL PPSRDELTKN QVSLTCLVKG FYPSDIAVEW ESNGQPENNY KTTPPVLDSD GSFFLYSKLT VDKSRWQQGN VFSCSVMHEA LHNHYTQKSL SLSPGKHHHH HH
- 纯度
- > 90 % by SDS - PAGE
- 内毒素水平
- < 1.0 EU per 1ug of protein (determined by LAL method)
- Top Product
- Discover our top product CD8B 蛋白
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CD8b Molecule (CD8B) (AA 1-243) protein (GST tag)
CD8B 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
CD8b Molecule (CD8B) (AA 23-131) protein (GST tag)CD8B 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
CD8b Molecule (CD8B) protein (Fc Tag)CD8B 宿主: 人 宿主: 人细胞 Recombinant >95 % as determined by reducing SDS-PAGE.
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.5 mg/mL
- 缓冲液
- Liquid. In Phosphate Buffered Saline ( pH 7.4) containing 50 % glycerol, 1 mM DTT
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- 抗原
- CD8B (CD8b Molecule (CD8B))
- 别名
- CD8B (CD8B 产品)
- 别名
- Cd8b Protein, Ly-3 Protein, Ly-C Protein, Lyt-3 Protein, CD8B1 Protein, LEU2 Protein, LY3 Protein, LYT3 Protein, P37 Protein, Cd8b1 Protein, CD8b molecule Protein, CD8 antigen, beta chain 1 Protein, Cd8b Protein, CD8B Protein, Cd8b1 Protein
- 背景
- JAM2, also known as junctional adhesion molecule B isoform 1, is a type 1 transmembrane receptor belonging to the immunoglobulin superfamily. This protein is expressed prominently on high endothelial venules of lymphoid organs where it is localized to the intercellular boundaries of high endothelial cells. It can function as an adhesive ligand for the T cell line J45 and can interact with GM-CSF/IL-4-delived peripheral blood dendritic cells. Also, it plays a role in the regulation of transendothelial migration. It binds to very late activation antigen (VLA)-4, a leucocyte integrin that contributes to rolling and firm adhesion of lymphocytes to endothelial cells through binding to vascular cell adhesion molecule (VCAM)-1. Recombinant human JAM2, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
- 分子量
- 50.7kDa (452aa) 50-70kDa (SDS-PAGE under reducing conditions.)
- NCBI登录号
- NP_067042
- UniProt
- P57087
- 途径
- TCR Signaling
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