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CD8B Protein (AA 22-170) (Fc Tag)

This Recombinant CD8B protein is expressed in HEK-293 Cells.
产品编号 ABIN7319847
发货至: 中国
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Quick Overview for CD8B Protein (AA 22-170) (Fc Tag) (ABIN7319847)

抗原

See all CD8B 蛋白
CD8B (CD8b Molecule (CD8B))

蛋白类型

Recombinant

宿主

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资源

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HEK-293 Cells

纯度

> 95 % as determined by reducing SDS-PAGE.
  • 产品特性

    AA 22-170

    标记

    This CD8B protein is labelled with Fc Tag.

    原理

    Recombinant Human CD8 Beta Chain/CD8B (C-Fc)

    序列

    Leu22-Pro170

    产品特性

    Recombinant Human T-Cell Surface Glycoprotein CD8 beta Chain is produced by our Mammalian expression system and the target gene encoding Leu22-Pro170 is expressed with a Fc tag at the C-terminus.

    过滤

    0.2 μm filtered

    内毒素水平

    < 1.0 EU per μg of the protein as determined by the LAL method.

    Biological Activity Comment

    Not validated for activity
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.
    Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization.

    储存条件

    4 °C,-20 °C,-80 °C

    储存方法

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

    有效期

    12 months
  • 抗原

    CD8B (CD8b Molecule (CD8B))

    别名

    CD8 Beta Chain/CD8B

    背景

    CD8B,CD8B1,CD8b,T-Cell Surface Glycoprotein CD8 Beta Chain,T-Cell Surface Glycoprotein CD8β Chain (CD8 Antigen) is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. CD8 Antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. Multiple alternatively spliced transcript variants encoding distinct membrane associated or secreted isoforms have been described. A pseudogene, also located on chromosome 2, has been identified.

    分子量

    Calculated MW: 43.7 kDa

    Observed MW: 50-60 kDa

    基因ID

    926

    UniProt

    P10966

    途径

    TCR Signaling
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