CD8B Protein (AA 22-170) (Fc Tag)
Our Local Distributor
北京 101111
Quick Overview for CD8B Protein (AA 22-170) (Fc Tag) (ABIN7319847)
抗原
See all CD8B 蛋白蛋白类型
宿主
资源
纯度
-
-
产品特性
- AA 22-170
-
标记
- This CD8B protein is labelled with Fc Tag.
-
原理
- Recombinant Human CD8 Beta Chain/CD8B (C-Fc)
-
序列
- Leu22-Pro170
-
产品特性
- Recombinant Human T-Cell Surface Glycoprotein CD8 beta Chain is produced by our Mammalian expression system and the target gene encoding Leu22-Pro170 is expressed with a Fc tag at the C-terminus.
-
过滤
- 0.2 μm filtered
-
内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
-
Biological Activity Comment
- Not validated for activity
-
-
-
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
缓冲液
-
Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization. -
储存条件
- 4 °C,-20 °C,-80 °C
-
储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
-
有效期
- 12 months
-
-
- CD8B (CD8b Molecule (CD8B))
-
别名
- CD8 Beta Chain/CD8B
-
背景
- CD8B,CD8B1,CD8b,T-Cell Surface Glycoprotein CD8 Beta Chain,T-Cell Surface Glycoprotein CD8β Chain (CD8 Antigen) is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. CD8 Antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. Multiple alternatively spliced transcript variants encoding distinct membrane associated or secreted isoforms have been described. A pseudogene, also located on chromosome 2, has been identified.
-
分子量
-
Calculated MW: 43.7 kDa
Observed MW: 50-60 kDa
-
基因ID
- 926
-
UniProt
- P10966
-
途径
- TCR Signaling
抗原
-