THOC7 Protein (AA 1-204) (His tag)
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- 抗原 See all THOC7 蛋白
- THOC7 (THO Complex 7 (THOC7))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-204
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宿主
- 人
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资源
- 大肠杆菌(E. Coli)
- 标记
- This THOC7 protein is labelled with His tag.
- 应用范围
- SDS-PAGE (SDS)
- 序列
- MGSSHHHHHH SSGLVPRGSH MGSMGAVTDD EVIRKRLLID GDGAGDDRRI NLLVKSFIKW CNSGSQEEGY SQYQRMLSTL SQCEFSMGKT LLVYDMNLRE MENYEKIYKE IECSIAGAHE KIAECKKQIL QAKRIRKNRQ EYDALAKVIQ HHPDRHETLK ELEALGKELE HLSHIKESVE DKLELRRKQF HVLLSTIHEL QQTLENDEKL SEVEEAQEAS METDPKP
- 纯度
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product THOC7 蛋白
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.5 mg/mL
- 缓冲液
- Liquid. In Phosphate buffered saline ( pH 7.4) containing, 50 % glycerol, 1 mM DTT
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- 抗原
- THOC7 (THO Complex 7 (THOC7))
- 别名
- THOC7 (THOC7 产品)
- 别名
- RGD1305475 Protein, NIF3L1BP1 Protein, fSAP24 Protein, 1500006O09Rik Protein, 9230101K24Rik Protein, Nif3l1bp1 Protein, THO complex 7 Protein, Thoc7 Protein, THOC7 Protein
- 背景
- THOC7 is required for efficient export of polyadenylated RNA. This protein acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway. The TREX complex is essential for the export of Kaposi's sarcoma-associated herpesvirus (KSHV) intronless mRNAs and infectious virus production. Recombinant human THOC7 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- 分子量
- 26.1kDa (227aa) confirmed by MALDI-TOF
- NCBI登录号
- NP_079351
- UniProt
- Q6I9Y2
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