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THOC7 产品

(THO Complex 7 (THOC7))

Categories

Component of the THO subcomplex of the TREX complex. The TREX complex specifically associates with spliced mRNA and not with unspliced pre-mRNA. It is recruited to spliced mRNAs by a transcription-independent mechanism. Binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export. The recruitment occurs via an interaction between ALYREF/THOC4 and the cap-binding protein NCBP1. DDX39B functions as a bridge between ALYREF/THOC4 and the THO complex (By similarity).

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Featured THOC7 Categories

THOC7 抗体

High quality antibodies with extensive validation data.

THOC7 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended THOC7 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse
Application WB, ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7236184
Quantity 200 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, FACS
Validations
  • (4)
  • (2)
Cat. No. ABIN1881883
Quantity 400 μL
Datasheet Datasheet
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Monkey, Pig, Rabbit, Rat
Application WB
Validations
  • (1)
Cat. No. ABIN6750143
Quantity 100 μL
Datasheet Datasheet

Recommended THOC7 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6234176
Quantity 96 tests
Datasheet Datasheet

Recommended THOC7 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7125373
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1322709
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3074477
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our THOC7 Products

Lee, Song, Smith, Kay: "Human corneal endothelial cells employ phosphorylation of p27(Kip1) at both Ser10 and Thr187 sites for FGF-2-mediated cell proliferation via PI 3-kinase." in: Investigative ophthalmology & visual science, Vol. 52, Issue 11, pp. 8216-23, (2011) (PubMed).

Ramachandran, Tran, Klebba-Faerber, Kardinal, Whetton, Tamura: "An ataxia-telangiectasia-mutated (ATM) kinase mediated response to DNA damage down-regulates the mRNA-binding potential of THOC5." in: RNA (New York, N.Y.), Vol. 17, Issue 11, pp. 1957-66, (2011) (PubMed).

El Bounkari, Guria, Klebba-Faerber, Claussen, Pieler, Griffiths, Whetton, Koch, Tamura: "Nuclear localization of the pre-mRNA associating protein THOC7 depends upon its direct interaction with Fms tyrosine kinase interacting protein (FMIP)." in: FEBS letters, Vol. 583, Issue 1, pp. 13-8, (2008) (PubMed).

Masuda, Das, Cheng, Hurt, Dorman, Reed: "Recruitment of the human TREX complex to mRNA during splicing." in: Genes & development, Vol. 19, Issue 13, pp. 1512-7, (2005) (PubMed).

Synonyms and alternative names related to THOC7

THO complex 7 (Thoc7), THO complex 7 (THOC7), 1500006O09Rik, 9230101K24Rik, fSAP24, NIF3L1BP1, Nif3l1bp1, RGD1305475

Protein level used designations for THOC7

  • THO complex subunit 7 homolog
  • NIF3L1-binding protein 1
  • Ngg1 interacting factor 3 like 1 binding protein 1
  • functional spliceosome-associated protein 24
  • hTREX30
  • ngg1-interacting factor 3-like protein 1-binding protein 1
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