PAX8 Protein (AA 1-287) (His tag)
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- 抗原 See all PAX8 蛋白
- PAX8 (Paired Box 8 (PAX8))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-287
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This PAX8 protein is labelled with His tag.
- 应用范围
- SDS-PAGE (SDS)
- 序列
- MGSSHHHHHH SSGLVPRGSH MGSMPHNSIR SGHGGLNQLG GAFVNGRPLP EVVRQRIVDL AHQGVRPCDI SRQLRVSHGC VSKILGRYYE TGSIRPGVIG GSKPKVATPK VVEKIGDYKR QNPTMFAWEI RDRLLAEGVC DNDTVPSVSS INRIIRTKVQ QPFNLPMDSC VATKSLSPGH TLIPSSAVTP PESPQSDSLG STYSINGLLG IAQPGSDKRK MDDSDQDSCR LSIDSQSSSS GPRKHLRTDA FSQHHLEPLE CPFERQHYPE AYASPSHTKG EQEVNTLAMP MATPPTPPTA RPGASPTPAC
- 纯度
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product PAX8 蛋白
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Paired Box 8 (PAX8) (AA 141-250) protein (GST tag)
PAX8 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Paired Box 8 (PAX8) (AA 243-450) protein (His tag)PAX8 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Paired Box 8 (PAX8) (AA 1-450) protein (GST tag)PAX8 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Paired Box 8 (PAX8) (AA 300-377) protein (GST tag)PAX8 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Paired Box 8 (PAX8) (AA 1-450) protein (Strep Tag)Crystallography grade PAX8 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, ELISA, SDS
Paired Box 8 (PAX8) (AA 1-457) protein (Strep Tag)Crystallography grade PAX8 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, ELISA, SDS
Paired Box 8 (PAX8) protein (Myc-DYKDDDDK Tag)PAX8 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.25 mg/mL
- 缓冲液
- Liquid. In Phosphate buffer saline ( pH 7.4) containing 20 % glycerol , 1 mM DTT
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- 抗原
- PAX8 (Paired Box 8 (PAX8))
- 别名
- PAX8 (PAX8 产品)
- 别名
- PAX8 Protein, XPax-8 Protein, XPax8 Protein, pax-8 Protein, PAX-8 Protein, Pax-8 Protein, paired box 8 Protein, paired box 8 L homeolog Protein, PAX8 Protein, pax8 Protein, Pax8 Protein, pax8.L Protein
- 背景
- Paired box protein Pax-8 isoform PAX8E, also known as PAX8, is expressed in the developing and adult thyroid, the developing secretory system and at lower levels, in the adult kidney. PAX8complexes with TTF-1 and TTF-2 to induce thyroid follicular cell differentiation and thyroid hormone biosynthesis by regulating the expression of sodium iodide symporter (NIS), thyroid peroxidase (TPO), thyroglobulin (TG) and the thyrotropin receptor (TSHR). Defects in PAX8 are the cause of congenital hypothyroidism non-goitrous type 2 (CHNG2). Recombinant human PAX8 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- 分子量
- 33.4 kDa (310aa) confirmed by MALDI-TOF
- NCBI登录号
- NP_054698
- UniProt
- Q06710
- 途径
- Thyroid Hormone Synthesis, Regulation of Hormone Metabolic Process, Stem Cell Maintenance, Tube Formation
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