PAX8 产品
(Paired Box 8 (PAX8))
Categories
This gene encodes a member of the paired box (PAX) family of transcription factors. Members of this gene family typically encode proteins that contain a paired box domain, an octapeptide, and a paired-type homeodomain. This nuclear protein is involved in thyroid follicular cell development and expression of thyroid-specific genes. Mutations in this gene have been associated with thyroid dysgenesis, thyroid follicular carcinomas and atypical follicular thyroid adenomas. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Mar 2010].
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Featured PAX8 Categories
PAX8 抗体
High quality antibodies with extensive validation data.
PAX8 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
PAX8 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended PAX8 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IF, IHC (p), IP, ICC, ChIP
Validations
- (2)
- (8)
Cat. No.
ABIN2855097
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, FACS, IF, StM
Validations
- (6)
Cat. No.
ABIN6940924
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, FACS
Validations
- (7)
Cat. No.
ABIN7193697
Quantity
0.1 mg
Datasheet
Datasheet
Recommended PAX8 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6969128
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Analytical Method
Qualitative DNA-Binding ELISA
Validations
Cat. No.
ABIN5648503
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6951205
Quantity
96 tests
Datasheet
Datasheet
Recommended PAX8 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN2752880
Quantity
2 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7124298
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1314083
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our PAX8 Products
: "PAX8 regulon in human ovarian cancer links lineage dependency with epigenetic vulnerability to HDAC inhibitors." in: eLife, Vol. 8, (2020) (PubMed).: "PTEN-knockdown disrupts the morphology, growth pattern and function of Nthy-Ori 3-1 cells by downregulating PAX8 expression." in: Oncology letters, Vol. 18, Issue 6, pp. 6732-6740, (2019) (PubMed).
: "GLIS3 is indispensable for TSH/TSHR-dependent thyroid hormone biosynthesis and follicular cell proliferation." in: The Journal of clinical investigation, (2018) (PubMed).
: "The PAX8 cistrome in epithelial ovarian cancer." in: Oncotarget, Vol. 8, Issue 65, pp. 108316-108332, (2018) (PubMed).
: "Renal cancer: new models and approach for personalizing therapy. ..." in: Journal of experimental & clinical cancer research : CR, Vol. 37, Issue 1, pp. 217, (2018) (PubMed).
: "BCOR-CCNB3 Undifferentiated Sarcoma-Does Immunohistochemistry Help in the Identification?" in: Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society, Vol. 20, Issue 4, pp. 321-329, (2017) (PubMed).
: "Epigenetic remodeling regulates transcriptional changes between ovarian cancer and benign precursors." in: JCI insight, Vol. 1, Issue 13, (2016) (PubMed).
: "Renal progenitors derived from human iPSCs engraft and restore function in a mouse model of acute kidney injury." in: Scientific reports, Vol. 5, pp. 8826, (2015) (PubMed).
: "Utility of paired box gene 8 (PAX8) expression in fluid and fine-needle aspiration cytology: an immunohistochemical study of metastatic ovarian serous carcinoma." in: Cancer cytopathology, Vol. 118, Issue 5, pp. 298-302, (2010) (PubMed).
: "Fluorescence in situ hybridization analysis using PAX8- and PPARG-specific probes reveals the presence of PAX8-PPARG translocation and 3p25 aneusomy in follicular thyroid neoplasms." in: Cancer genetics and cytogenetics, Vol. 196, Issue 1, pp. 7-13, (2009) (PubMed).
Synonyms and alternative names related to PAX8
paired box 8 (PAX8), paired box 8 (pax8), paired box 8 (Pax8), paired box 8 L homeolog (pax8.L), pax-8, PAX-8, Pax-8, PAX8, XPax-8, XPax8Protein level used designations for PAX8
- paired box 8
- paired box gene 8
- paired box protein Pax-8
- paired domain gene 8
- Pax-8 protein
- Pax-8 DNA-binding transcription factor
- XPax-8
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