BCCIP Protein (AA 1-314) (His tag)
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- 抗原 See all BCCIP 蛋白
- BCCIP (BRCA2 and CDKN1A Interacting Protein (BCCIP))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-314
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This BCCIP protein is labelled with His tag.
- 应用范围
- SDS-PAGE (SDS)
- 序列
- MGSSHHHHHH SSGLVPRGSH MGSEFMASRS KRRAVESGVP QPPDPPVQRD EEEEKEVENE DEDDDDSDKE KDEEDEVIDE EVNIEFEAYS LSDNDYDGIK KLLQQLFLKA PVNTAELTDL LIQQNHIGSV IKQTDVSEDS NDDMDEDEVF GFISLLNLTE RKGTQCVEQI QELVLRFCEK NCEKSMVEQL DKFLNDTTKP VGLLLSERFI NVPPQIALPM YQQLQKELAG AHRTNKPCGK CYFYLLISKT FVEAGKNNSK KKPSNKKKAA LMFANAEEEF FYEKAILKFN YSVQEESDTC LGGKWSFDDV PMTPLRTVML IPGDKMNEIM DKLKEYLSV
- 纯度
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product BCCIP 蛋白
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BRCA2 and CDKN1A Interacting Protein (BCCIP) (AA 1-314) protein (His tag)
BCCIP 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
BRCA2 and CDKN1A Interacting Protein (BCCIP) (AA 1-314) protein (GST tag)BCCIP 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP
BRCA2 and CDKN1A Interacting Protein (BCCIP) (AA 210-314) protein (GST tag)BCCIP 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP
BRCA2 and CDKN1A Interacting Protein (BCCIP) (Transcript Variant B) protein (Myc-DYKDDDDK Tag)BCCIP 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.5 mg/mL
- 缓冲液
- Liquid. In 20 mM Tris-HCl buffer ( pH 8.0) containing 0.15M NaCl, 10 % glycerol, 1 mM DTT
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- 抗原
- BCCIP (BRCA2 and CDKN1A Interacting Protein (BCCIP))
- 别名
- BCCIP (BCCIP 产品)
- 别名
- zgc:110272 Protein, mp:zf637-1-000774 Protein, BCCIP Protein, DKFZp459K2416 Protein, MGC82792 Protein, tok-1 Protein, MGC89311 Protein, TOK-1 Protein, TOK1 Protein, 1110013J05Rik Protein, BRCA2 and CDKN1A interacting protein Protein, BRCA2 and CDKN1A interacting protein L homeolog Protein, BCCIP Protein, bccip Protein, bccip.L Protein, Bccip Protein
- 背景
- BCCIP was isolated on the basis of its interaction with BRCA2 and p21 proteins. It is an evolutionarily conserved nuclear protein with multiple interacting domains. The N-terminal half shares moderate homology with regions of calmodulin and M-calpain, suggesting that it may also bind calcium. Functional studies indicate that this protein may be an important cofactor for BRCA2 in tumor suppression, and a modulator of CDK2 kinase activity via p21. This protein has also been implicated in the regulation of BRCA2 and RAD51 nuclear focus formation, double-strand break-induced homologous recombination, and cell cycle progression. Recombinant human BCCIP protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- 分子量
- 38.6kDa(339aa), confirmed by MALDI-TOF (Molecular size on SDS-PAGE will appear higher)
- NCBI登录号
- NP_510868
- UniProt
- Q9P287
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