BCCIP Protein (Transcript Variant B) (Myc-DYKDDDDK Tag)
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- 抗原 See all BCCIP 蛋白
- BCCIP (BRCA2 and CDKN1A Interacting Protein (BCCIP))
- 蛋白类型
- Recombinant
- 产品特性
- Transcript Variant B
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This BCCIP protein is labelled with Myc-DYKDDDDK Tag.
- 应用范围
- Antibody Production (AbP), Standard (STD)
- 产品特性
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- Recombinant human BCCIP / TOK1 (transcript variant B) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product BCCIP 蛋白
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BRCA2 and CDKN1A Interacting Protein (BCCIP) (AA 1-314) protein (His tag)
BCCIP 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
BRCA2 and CDKN1A Interacting Protein (BCCIP) (AA 1-314) protein (GST tag)BCCIP 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP
BRCA2 and CDKN1A Interacting Protein (BCCIP) (AA 210-314) protein (GST tag)BCCIP 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP
BRCA2 and CDKN1A Interacting Protein (BCCIP) (AA 1-314) protein (Strep Tag)Crystallography grade BCCIP 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
BRCA2 and CDKN1A Interacting Protein (BCCIP) (AA 1-316) protein (Strep Tag)Crystallography grade BCCIP 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
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- 应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - 说明
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The tag is located at the C-terminal.
- 限制
- 仅限研究用
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- 浓度
- 50 μg/mL
- 缓冲液
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- 抗原
- BCCIP (BRCA2 and CDKN1A Interacting Protein (BCCIP))
- 别名
- Bccip,tok1 (BCCIP 产品)
- 别名
- zgc:110272 Protein, mp:zf637-1-000774 Protein, BCCIP Protein, DKFZp459K2416 Protein, MGC82792 Protein, tok-1 Protein, MGC89311 Protein, TOK-1 Protein, TOK1 Protein, 1110013J05Rik Protein, BRCA2 and CDKN1A interacting protein Protein, BRCA2 and CDKN1A interacting protein L homeolog Protein, BCCIP Protein, bccip Protein, bccip.L Protein, Bccip Protein
- 背景
- This gene product was isolated on the basis of its interaction with BRCA2 and p21 proteins. It is an evolutionarily conserved nuclear protein with multiple interacting domains. The N-terminal half shares moderate homology with regions of calmodulin and M-calpain, suggesting that it may also bind calcium. Functional studies indicate that this protein may be an important cofactor for BRCA2 in tumor suppression, and a modulator of CDK2 kinase activity via p21. This protein has also been implicated in the regulation of BRCA2 and RAD51 nuclear focus formation, double-strand break-induced homologous recombination, and cell cycle progression. Multiple transcript variants encoding different isoforms have been described for this gene.
- 分子量
- 35.8 kDa
- NCBI登录号
- NP_510868
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