SIRT1 Protein (AA 254-495) (His tag)
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- 抗原 See all SIRT1 蛋白
- SIRT1 (Sirtuin 1 (SIRT1))
- 蛋白类型
- Recombinant
- 产品特性
- AA 254-495
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This SIRT1 protein is labelled with His tag.
- 应用范围
- SDS-PAGE (SDS)
- 序列
- MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSHMKK IIVLTGAGVS VSCGIPDFRS RDGIYARLAV DFPDLPDPQA MFDIEYFRKD PRPFFKFAKE IYPGQFQPSL CHKFIALSDK EGKLLRNYTQ NIDTLEQVAG IQRIIQCHGS FATASCLICK YKVDCEAVRG DIFNQVVPRC PRCPADEPLA IMKPEIVFFG ENLPEQFHRA MKYDKDEVDL LIVIGSSLKV RPVALIPSSI PHEVPQILIN REPLPHLHFD VELLGDCDVI INELCHRLGG
- 纯度
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product SIRT1 蛋白
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Sirtuin 1 (SIRT1) (AA 510-747) protein (His tag)
SIRT1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Sirtuin 1 (SIRT1) (AA 456-555) protein (GST tag)SIRT1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Sirtuin 1 (SIRT1) (AA 2-533) protein (His tag)Crystallography grade SIRT1 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Sirtuin 1 (SIRT1) (AA 2-525) protein (His tag)Crystallography grade SIRT1 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Sirtuin 1 (SIRT1) (AA 2-747) protein (His tag)Crystallography grade SIRT1 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Sirtuin 1 (SIRT1) (AA 2-737) protein (His tag)Crystallography grade SIRT1 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 说明
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Denatured
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.5 mg/mL
- 缓冲液
- Liquid. In 20 mM Tris-HCl buffer ( pH 8.0) containing 10 % glycerol, 0.4M urea
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- 抗原
- SIRT1 (Sirtuin 1 (SIRT1))
- 别名
- SIRT1 (SIRT1 产品)
- 别名
- sirtuin 1 Protein, AA673258 Protein, SIR2L1 Protein, Sir2 Protein, Sir2a Protein, Sir2alpha Protein, sir2l1 Protein, sirtuin Protein, SIR2 Protein, sirtuin 1 Protein, sirtuin 1 L homeolog Protein, SIRT1 Protein, SRT1 Protein, Sirt1 Protein, sirt1.L Protein
- 背景
- SIRT1 is a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined, however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. Alternative splicing results in multiple transcript variants. Recombinant human SIRT1 protein, fused to His-tag at N-terminus, was expressed in E.coli .
- 分子量
- 31.6 kDa (280 aa)
- NCBI登录号
- NP_036370
- UniProt
- Q96EB6
- 途径
- MAPK Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Carbohydrate Homeostasis, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus, Negative Regulation of intrinsic apoptotic Signaling
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